CEBPA Antibody - N-terminal region (P100908_P050)

Data Sheet
 
Product Number P100908_P050
Product Page www.avivasysbio.com/cebpa-antibody-n-terminal-region-p100908-p050.html
Name CEBPA Antibody - N-terminal region (P100908_P050)
Protein Size (# AA) 358 amino acids
Molecular Weight 38kDa
NCBI Gene Id 1050
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name CCAAT/enhancer binding protein (C/EBP), alpha
Description
Alias Symbols CEBP, C/EBP-alpha
Peptide Sequence Synthetic peptide located within the following region: GGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Zhu,Q.S., et al., (2004) J. Biol. Chem. 279 (29), 29902-29910
Description of Target CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Protein Interactions CEBPB; ZBTB16; RARA; HDAC1; BHLHE41; UBC; CEBPE; BATF2; BATF3; YY1AP1; ATF5; BATF; FOSL1; FOS; DBP; CEBPG; CEBPA; ATF4; ATF3; UBE3A; SKP2; RASGRF1; C1QBP; CDKN1A; SRA1; CDK4; PIAS1; Fbxw7; GRIN3A; RAB34; NAA16; POLR1E; MRTO4; AK5; MACF1; KAT5; AKAP9; SMC1
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CEBPA (P100908_P050) antibody
Blocking Peptide For anti-CEBPA (P100908_P050) antibody is Catalog # AAP31256 (Previous Catalog # AAPP02005)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA
Uniprot ID P49715
Protein Name CCAAT/enhancer-binding protein alpha
Sample Type Confirmation

CEBPA is supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_004355
Purification Affinity Purified
Nucleotide Accession # NM_004364
Tested Species Reactivity Human
Gene Symbol CEBPA
Predicted Species Reactivity Human, Mouse, Rat, Cow, Guinea Pig, Pig
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Image 1
Human HepG2
WB Suggested Anti-CEBPA Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateCEBPA is supported by BioGPS gene expression data to be expressed in HepG2
 

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