TCF3 Antibody - C-terminal region (P100871_T100)

Data Sheet
 
Product Number P100871_T100
Product Page www.avivasysbio.com/tcf3-antibody-c-terminal-region-p100871-t100.html
Name TCF3 Antibody - C-terminal region (P100871_T100)
Protein Size (# AA) 440 amino acids
Molecular Weight 48kDa
NCBI Gene Id 6929
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
Description
Alias Symbols E2A, E47, p75, AGM8, ITF1, VDIR, TCF-3, bHLHb21
Peptide Sequence Synthetic peptide located within the following region: EENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVAN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Protein Interactions ID3; FAM115A; TLE1; RNF14; UBC; SCX; MAPKAPK2; MAPKAPK3; TCF21; Ube2i; ID2; FUS; CTNNB1; RPL37; MAX; USF1; TCF12; TCF3; MYOD1; Rufy1; Tfap4; Rpa1; Tbx6; Ncl; Twist2; SUPT3H; TRRAP; KAT2A; TADA2A; FOXH1; ELAVL1; TCF24; SETSIP; FLG2; BHLHA15; MYL6B; TIMM50;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TCF3 (P100871_T100) antibody
Blocking Peptide For anti-TCF3 (P100871_T100) antibody is Catalog # AAP31083 (Previous Catalog # AAPP01822)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TCF3
Uniprot ID P15923
Protein Name Transcription factor E2-alpha
Sample Type Confirmation

TCF3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # AAA56830
Purification Protein A purified
Nucleotide Accession # NM_001136139
Tested Species Reactivity Human
Gene Symbol TCF3
Predicted Species Reactivity Human, Mouse, Rat, Dog, Guinea Pig, Pig
Application WB
Predicted Homology Based on Immunogen Sequence Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rat: 100%
Image 1
Human Jurkat
WB Suggested Anti-TCF3 Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysateTCF3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
 

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