Product Number |
P100832_T100 |
Product Page |
www.avivasysbio.com/gabpa-antibody-c-terminal-region-p100832-t100.html |
Name |
GABPA Antibody - C-terminal region (P100832_T100) |
Protein Size (# AA) |
454 amino acids |
Molecular Weight |
51kDa |
NCBI Gene Id |
2551 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
GA binding protein transcription factor, alpha subunit 60kDa |
Description |
|
Alias Symbols |
NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07 |
Peptide Sequence |
Synthetic peptide located within the following region: KWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIG |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Xue, H.H., et al., (2004) Nat.Immunol.5(10),1036-1044 |
Description of Target |
GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. |
Protein Interactions |
UBC; NCOA7; KCTD12; TSEN34; DIABLO; CUTC; RAB3GAP2; LIMCH1; RAB3GAP1; GNE; KPNA1; YY1; GABPB1; PINX1; APP; KEAP1; SUMO2; HDAC1; EP300; SP3; CREBBP; HCFC1; SP1; ATF1; MED1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-GABPA (P100832_T100) antibody |
Blocking Peptide |
For anti-GABPA (P100832_T100) antibody is Catalog # AAP31187 (Previous Catalog # AAPP01930) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GABPA |
Uniprot ID |
Q06546 |
Protein Name |
GA-binding protein alpha chain |
Sample Type Confirmation |
GABPA is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_002031 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_002040 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
GABPA |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human kidney
| Human kidney |
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Image 2 | Mouse Testis
| Host: Mouse Target Name: GABPA Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml |
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Image 3 | Human Jurkat
| WB Suggested Anti-GABPA Antibody Titration: 0.5-1.0ug/ml Positive Control: Jurkat cell lysateGABPA is supported by BioGPS gene expression data to be expressed in Jurkat |
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