GABPA Antibody - C-terminal region (P100832_T100)

Data Sheet
 
Product Number P100832_T100
Product Page www.avivasysbio.com/gabpa-antibody-c-terminal-region-p100832-t100.html
Name GABPA Antibody - C-terminal region (P100832_T100)
Protein Size (# AA) 454 amino acids
Molecular Weight 51kDa
NCBI Gene Id 2551
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name GA binding protein transcription factor, alpha subunit 60kDa
Description
Alias Symbols NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07
Peptide Sequence Synthetic peptide located within the following region: KWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Xue, H.H., et al., (2004) Nat.Immunol.5(10),1036-1044
Description of Target GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
Protein Interactions UBC; NCOA7; KCTD12; TSEN34; DIABLO; CUTC; RAB3GAP2; LIMCH1; RAB3GAP1; GNE; KPNA1; YY1; GABPB1; PINX1; APP; KEAP1; SUMO2; HDAC1; EP300; SP3; CREBBP; HCFC1; SP1; ATF1; MED1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-GABPA (P100832_T100) antibody
Blocking Peptide For anti-GABPA (P100832_T100) antibody is Catalog # AAP31187 (Previous Catalog # AAPP01930)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human GABPA
Uniprot ID Q06546
Protein Name GA-binding protein alpha chain
Sample Type Confirmation

GABPA is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_002031
Purification Protein A purified
Nucleotide Accession # NM_002040
Tested Species Reactivity Human, Mouse
Gene Symbol GABPA
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human kidney
Human kidney
Image 2
Mouse Testis
Host: Mouse
Target Name: GABPA
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml
Image 3
Human Jurkat
WB Suggested Anti-GABPA Antibody Titration: 0.5-1.0ug/ml
Positive Control: Jurkat cell lysateGABPA is supported by BioGPS gene expression data to be expressed in Jurkat
 

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