Product Number |
P100797_T100 |
Product Page |
www.avivasysbio.com/sox9-antibody-n-terminal-region-p100797-t100.html |
Name |
SOX9 Antibody - N-terminal region (P100797_T100) |
Protein Size (# AA) |
509 amino acids |
Molecular Weight |
56 kDa |
NCBI Gene Id |
6662 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
SRY (sex determining region Y)-box 9 |
Description |
|
Alias Symbols |
CMD1, SRA1, CMPD1, SRXX2, SRXY10 |
Peptide Sequence |
Synthetic peptide located within the following region: PCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQVLKG |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Furumatsu,T., et al., (2005) J. Biol. Chem. 280 (42), 35203-35208 |
Description of Target |
SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. |
Protein Interactions |
ZBTB7A; SCX; HERC1; UBC; SOX9; ATP6V1H; ctnnb1-a; RUNX2; SMAD3; SMAD2; EP300; CREB3L4; SPEN; KPNB1; TRAF2; CREBBP; MED12; NR5A1; MAF; HSPA1A; CREB1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
|
Datasheets/Manuals |
Printable datasheet for anti-SOX9 (P100797_T100) antibody |
Blocking Peptide |
For anti-SOX9 (P100797_T100) antibody is Catalog # AAP31138 (Previous Catalog # AAPP01877) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SOX9 |
Uniprot ID |
P48436 |
Protein Name |
Transcription factor SOX-9 |
Publications |
Ferrand, N. et al. Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype. PLoS One 9, e87878 (2014). WB, Human, Mouse 24498388 |
Sample Type Confirmation |
SOX9 is strongly supported by BioGPS gene expression data to be expressed in HepG2 |
Protein Accession # |
NP_000337 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_000346 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
SOX9 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
Image 1 | Mouse Brain
| Host: Rabbit Target Name: SOX9 Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml |
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