Product Number |
P100692_T100 |
Product Page |
www.avivasysbio.com/eloa-antibody-c-terminal-region-p100692-t100.html |
Name |
ELOA Antibody - C-terminal region (P100692_T100) |
Protein Size (# AA) |
772 amino acids |
Molecular Weight |
87kDa |
NCBI Gene Id |
6924 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
elongin A |
Description |
|
Alias Symbols |
SIII, TCEB3, TCEB3A, SIII p110 |
Peptide Sequence |
Synthetic peptide located within the following region: AYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 |
Description of Target |
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. |
Protein Interactions |
KRTAP10-3; CEP57L1; SPERT; FAM9B; KRT40; CEP70; GMCL1; HOMEZ; TRIM54; MID2; PLK4; JAKMIP2; PSMB9; POLR2L; POLR2K; POLR2J; POLR2I; POLR2H; POLR2G; POLR2F; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; MDFI; UBC; RAD54B; MED26; ECT2; BARD1; CDK12; TCEB2; TCEB1; B |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ELOA (P100692_T100) antibody |
Blocking Peptide |
For anti-ELOA (P100692_T100) antibody is Catalog # AAP31037 (Previous Catalog # AAPP01770) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human TCEB3 |
Uniprot ID |
Q14241 |
Protein Name |
elongin-A |
Sample Type Confirmation |
TCEB3 is strongly supported by BioGPS gene expression data to be expressed in HEK293T |
Protein Accession # |
NP_003189 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_003198 |
Tested Species Reactivity |
Human |
Gene Symbol |
ELOA |
Predicted Species Reactivity |
Rat, Dog, Guinea Pig |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 91%; Rat: 92% |
Image 1 | Human pancreas
| Human Pancrease |
|
Image 2 | Human HEK293T
| WB Suggested Anti-TCEB3 Antibody Titration: 7.5ug/ml Positive Control: Transfected 293TTCEB3 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells |
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