ELOA Antibody - C-terminal region (P100692_T100)

Data Sheet
 
Product Number P100692_T100
Product Page www.avivasysbio.com/eloa-antibody-c-terminal-region-p100692-t100.html
Name ELOA Antibody - C-terminal region (P100692_T100)
Protein Size (# AA) 772 amino acids
Molecular Weight 87kDa
NCBI Gene Id 6924
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name elongin A
Description
Alias Symbols SIII, TCEB3, TCEB3A, SIII p110
Peptide Sequence Synthetic peptide located within the following region: AYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Description of Target This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Protein Interactions KRTAP10-3; CEP57L1; SPERT; FAM9B; KRT40; CEP70; GMCL1; HOMEZ; TRIM54; MID2; PLK4; JAKMIP2; PSMB9; POLR2L; POLR2K; POLR2J; POLR2I; POLR2H; POLR2G; POLR2F; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; MDFI; UBC; RAD54B; MED26; ECT2; BARD1; CDK12; TCEB2; TCEB1; B
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ELOA (P100692_T100) antibody
Blocking Peptide For anti-ELOA (P100692_T100) antibody is Catalog # AAP31037 (Previous Catalog # AAPP01770)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TCEB3
Uniprot ID Q14241
Protein Name elongin-A
Sample Type Confirmation

TCEB3 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Protein Accession # NP_003189
Purification Protein A purified
Nucleotide Accession # NM_003198
Tested Species Reactivity Human
Gene Symbol ELOA
Predicted Species Reactivity Rat, Dog, Guinea Pig
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 100%; Guinea Pig: 91%; Rat: 92%
Image 1
Human pancreas
Human Pancrease
Image 2
Human HEK293T
WB Suggested Anti-TCEB3 Antibody Titration: 7.5ug/ml
Positive Control: Transfected 293TTCEB3 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells
 

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