Product Number |
P100613_P050 |
Product Page |
www.avivasysbio.com/irf2-antibody-n-terminal-region-p100613-p050.html |
Name |
IRF2 Antibody - N-terminal region (P100613_P050) |
Protein Size (# AA) |
349 amino acids |
Molecular Weight |
39kDa |
NCBI Gene Id |
3660 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Interferon regulatory factor 2 |
Description |
|
Alias Symbols |
IRF-2 |
Peptide Sequence |
Synthetic peptide located within the following region: APLFRNRAIHTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Oshima,S., et al., (2004) Mol. Cell. Biol. 24 (14), 6298-6310 |
Description of Target |
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. |
Protein Interactions |
IRF1; SUMO2; SUMO3; PRDM1; MDM2; FKBP7; HSP90AA1; APP; IRF2BP2; IRF2BP1; UBC; FOXK1; IRF2BPL; HCFC2; ATG7; AP5Z1; PPP3CB; PPP3CA; FOXK2; HCFC1; KAT2B; EP300; IRF8; STAT1; RELA; NFKB1; HMGN1; HMGB1; CSNK2A1; BRD7; PRKACA; KAT2A; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-IRF2 (P100613_P050) antibody |
Blocking Peptide |
For anti-IRF2 (P100613_P050) antibody is Catalog # AAP30923 (Previous Catalog # AAPP01647) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human IRF2 |
Uniprot ID |
P14316 |
Protein Name |
Interferon regulatory factor 2 |
Protein Accession # |
NP_002190 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_002199 |
Tested Species Reactivity |
Human |
Gene Symbol |
IRF2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Zebrafish |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rat: 100%; Sheep: 92%; Zebrafish: 90% |
Image 1 | Human heart
| Rabbit Anti-IRF2 Antibody Catalog Number: P100613_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
|
Image 2 | Human Jurkat
| WB Suggested Anti-IRF2 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysate |
|