IRF2 Antibody - N-terminal region (P100613_P050)

Data Sheet
 
Product Number P100613_P050
Product Page www.avivasysbio.com/irf2-antibody-n-terminal-region-p100613-p050.html
Name IRF2 Antibody - N-terminal region (P100613_P050)
Protein Size (# AA) 349 amino acids
Molecular Weight 39kDa
NCBI Gene Id 3660
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Interferon regulatory factor 2
Description
Alias Symbols IRF-2
Peptide Sequence Synthetic peptide located within the following region: APLFRNRAIHTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Oshima,S., et al., (2004) Mol. Cell. Biol. 24 (14), 6298-6310
Description of Target IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Protein Interactions IRF1; SUMO2; SUMO3; PRDM1; MDM2; FKBP7; HSP90AA1; APP; IRF2BP2; IRF2BP1; UBC; FOXK1; IRF2BPL; HCFC2; ATG7; AP5Z1; PPP3CB; PPP3CA; FOXK2; HCFC1; KAT2B; EP300; IRF8; STAT1; RELA; NFKB1; HMGN1; HMGB1; CSNK2A1; BRD7; PRKACA; KAT2A;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-IRF2 (P100613_P050) antibody
Blocking Peptide For anti-IRF2 (P100613_P050) antibody is Catalog # AAP30923 (Previous Catalog # AAPP01647)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IRF2
Uniprot ID P14316
Protein Name Interferon regulatory factor 2
Protein Accession # NP_002190
Purification Affinity Purified
Nucleotide Accession # NM_002199
Tested Species Reactivity Human
Gene Symbol IRF2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Zebrafish
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rat: 100%; Sheep: 92%; Zebrafish: 90%
Image 1
Human heart
Rabbit Anti-IRF2 Antibody
Catalog Number: P100613_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Image 2
Human Jurkat
WB Suggested Anti-IRF2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
 

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