| Product Number |
OPPA01634 |
| Product Page |
www.avivasysbio.com/il-17-protein-oppa01634.html |
| Name |
IL 17 Protein (OPPA01634) |
| Protein Size (# AA) |
Recombinant amino acids |
| NCBI Gene Id |
25465 |
| Host |
E. Coli |
| Purity |
Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Alias Symbols |
Il17 |
| Peptide Sequence |
MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS. |
| Product Format |
Lyophilized from a concentrated (1mg/ml) solution containing 10mM NaCitrate, pH-3.0. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder. |
| Description of Target |
Recombinant Rat Interleukin-17A |
| Reconstitution and Storage |
Lyophilized Interleukin Rat 17A although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Rat IL17 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OPPA01634 |
| Additional Information |
Solubility: It is recommended to reconstitute the lyophilized Interleukin Rat 17A in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. |
| Additional Information |
Biological Activity: Rat IL-17A is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured rat fibroblasts. |
| Additional Information |
Product Introduction: IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Product Description: Interleukin-17A Rat Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain having a molecular mass of 30 kDa. The IL-17A Rat is purified by proprietary chromatographic techniques. |
| Uniprot ID |
Q61453 |
| Protein Name |
Interleukin-17A |
| Gene Symbol |
IL17 |
| Predicted Species Reactivity |
Rat |
| Image 1 | |
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