| Product Number |
OPPA01630 |
| Product Page |
www.avivasysbio.com/il-1-beta-protein-oppa01630.html |
| Name |
IL 1 beta Protein (OPPA01630) |
| Protein Size (# AA) |
Recombinant amino acids |
| NCBI Gene Id |
16176 |
| Host |
E. Coli |
| Purity |
Greater than 90.0% as determined by SDS-PAGE. |
| Alias Symbols |
IL-, Il-1b, IL-1beta |
| Peptide Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS. |
| Product Format |
The IL-1B protein contains 20mM Tris pH-8 and 10% glycerol. Physical appearance: Sterile Filtered colorless solution. |
| Description of Target |
Recombinant Mouse Interleukin-1 beta, His Tag |
| Reconstitution and Storage |
IL-1b although stable at 4C for 2 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OPPA01630 |
| Additional Information |
Product Introduction: Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1b is an inflammatory cytokine which modulates angiogenesis by interacting directly with vascular endothelial cells & increasing the production of proangiogenic factors through paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL1B is essential for tumor growth, metastasis, and angiogenesis in quite a few animal models.
Product Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques. |
| Uniprot ID |
P10749 |
| Protein Name |
Interleukin-1 beta |
| Protein Accession # |
NP_032387.1 |
| Gene Symbol |
IL1-Beta |
| Predicted Species Reactivity |
Mouse |
| Image 1 | |
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