SNAI2 Antibody (OAEC04613)

Data Sheet
 
Product Number OAEC04613
Product Page www.avivasysbio.com/snai2-antibody-oaec04613.html
Name SNAI2 Antibody (OAEC04613)
Molecular Weight 30 kDa
Clone 2H5
Isotype IgG1
NCBI Gene Id 6591
Host Mouse
Clonality Monoclonal
Concentration 1 mg/ml
Gene Full Name snail family zinc finger 2
Alias Symbols SLUG, WS2D, SLUGH, SLUGH1, SNAIL2
Product Format Liquid. Ascitic fluid containing 0.03% sodium azide
Description of Target This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors . The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchym al transitions and has antiapoptotic activity.The tum or suppressor protein p53 induces Slug expres sion in gamma -irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Reconstitution and Storage Store at 4C, for long term storage, store at -20C.
Datasheets/Manuals Printable datasheet for anti-SNAI2 (OAEC04613) antibody
Application Info WB: 1/500-1/2000
ELISA: 1/10000
Immunogen Purified recombinant fragment of human SNAI2 expressed in E. Coli.
Uniprot ID O43623
Gene Symbol SNAI2
Predicted Species Reactivity Human
Application WB
Image 1
SNAI2-hIgGFc transfected HEK293 cell lysate
Western blot analysis using SNAI2 mouse mAb against SNAI2-hIgGFc transfected HEK293 cell lysate.
 

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