Product Number |
OAEC04613 |
Product Page |
www.avivasysbio.com/snai2-antibody-oaec04613.html |
Name |
SNAI2 Antibody (OAEC04613) |
Molecular Weight |
30 kDa |
Clone |
2H5 |
Isotype |
IgG1 |
NCBI Gene Id |
6591 |
Host |
Mouse |
Clonality |
Monoclonal |
Concentration |
1 mg/ml |
Gene Full Name |
snail family zinc finger 2 |
Alias Symbols |
SLUG, WS2D, SLUGH, SLUGH1, SNAIL2 |
Product Format |
Liquid. Ascitic fluid containing 0.03% sodium azide |
Description of Target |
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors . The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchym al transitions and has antiapoptotic activity.The tum or suppressor protein p53 induces Slug expres sion in gamma -irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects. |
Reconstitution and Storage |
Store at 4C, for long term storage, store at -20C. |
Datasheets/Manuals |
Printable datasheet for anti-SNAI2 (OAEC04613) antibody |
Application Info |
WB: 1/500-1/2000 ELISA: 1/10000 |
Immunogen |
Purified recombinant fragment of human SNAI2 expressed in E. Coli. |
Uniprot ID |
O43623 |
Gene Symbol |
SNAI2 |
Predicted Species Reactivity |
Human |
Application |
WB |
Image 1 | SNAI2-hIgGFc transfected HEK293 cell lysate
| Western blot analysis using SNAI2 mouse mAb against SNAI2-hIgGFc transfected HEK293 cell lysate. |
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