| Product Number |
AVARP13086_T100 |
| Product Page |
www.avivasysbio.com/gdi1-antibody-c-terminal-region-avarp13086-t100.html |
| Name |
GDI1 Antibody - C-terminal region (AVARP13086_T100) |
| Protein Size (# AA) |
447 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
2664 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
GDP dissociation inhibitor 1 |
| Alias Symbols |
1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA |
| Peptide Sequence |
Synthetic peptide located within the following region: VFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Papaharalambus,C., et al., (2005) J. Biol. Chem. 280 (19), 18790-18796 |
| Description of Target |
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. |
| Protein Interactions |
LNX1; UBC; RCC2; DCUN1D1; ACOT7; GGH; HIST1H2BO; SGTA; NEDD8; HEXA; GNAI2; ASL; ALDH9A1; SCRN1; GINS3; IQCB1; GNL1; RAB11B; RAB1A; PCMT1; UBQLN4; CUL5; CDK2; SIRT7; MINOS1; TK1; RAB24; RAB1B; RABAC1; RAB27A; RAC2; RHOH; RAB9A; RAB6A; EPB41; CDC42; PSEN1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GDI1 (AVARP13086_T100) antibody |
| Blocking Peptide |
For anti-GDI1 (AVARP13086_T100) antibody is Catalog # AAP30750 (Previous Catalog # AAPP01411) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GDI1 |
| Uniprot ID |
P31150 |
| Protein Name |
Rab GDP dissociation inhibitor alpha |
| Protein Accession # |
NP_001484 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001493 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
GDI1 |
| Predicted Species Reactivity |
Human, Mouse, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Sheep: 92%; Zebrafish: 92% |
| Image 1 | Human , Mouse
 | Human, Mouse |
|
| Image 2 | Human HepG2
 | WB Suggested Anti-GDI1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
| Image 3 | Mouse Heart
 | Host: Mouse
Target Name: GDI1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml |
|
