CHRNA2 Antibody - N-terminal region (AVARP13064_T100)

• Product Number: AVARP13064_T100
• Name: CHRNA2 Antibody - N-terminal region (AVARP13064_T100)
• Protein Size (# AA): 529 amino acids
• Molecular Weight: 60kDa
• Subunit: alpha-2
• NCBI Gene Id: 1135
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: Cholinergic receptor, nicotinic, alpha 2 (neuronal)
• Peptide Sequence: Synthetic peptide located within the following region: TKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDR
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Elliott, K. J., et al., (1996) J. Mol. Neurosci. 7:217-228.
• Description of Target: After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
• Protein Interactions: CHRNB4; CHRNB2;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-CHRNA2 (AVARP13064_T100) antibody is Catalog # AAP30669 (Previous Catalog # AAPP01326)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA2
• Uniprot ID: Q15822
• Protein Name: Neuronal acetylcholine receptor subunit alpha-2
• Protein Accession #: NP_000733
• Purification: Protein A purified
• Nucleotide Accession #: NM_000742
• Tested Species Reactivity: Human
• Gene Symbol: CHRNA2
• Predicted Species Reactivity: Human
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Image 1: HepG2, Raji
  
  Host: Rabbit
  Target Name: CHRNA2 Lane A: HepG2 cell lysates Lane B: Raji cell lysates
  Antibody Dilution: 0.5ug/ml