Product Number |
AVARP13049_T100 |
Product Page |
www.avivasysbio.com/napa-antibody-n-terminal-region-avarp13049-t100.html |
Name |
NAPA Antibody - N-terminal region (AVARP13049_T100) |
Protein Size (# AA) |
295 amino acids |
Molecular Weight |
33kDa |
NCBI Gene Id |
8775 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
N-ethylmaleimide-sensitive factor attachment protein, alpha |
Alias Symbols |
SNAPA |
Peptide Sequence |
Synthetic peptide located within the following region: MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAAN |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Lemons, P.P., et al., (1997) Blood 90 (4), 1490-1500. |
Description of Target |
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. |
Protein Interactions |
UBC; RPA3; RPA2; RPA1; RNF2; ATP4A; STX5; ITGA4; FN1; VCAM1; VCP; DHX40; DHX29; THUMPD3; STAM2; VAMP2; APP; NSF; TRPC3; RTN4; STX12; GNA12; STX8; GOSR2; GOSR1; BNIP1; STX7; VAMP8; SNAP23; STX4; STX1A; SNAP25; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-NAPA (AVARP13049_T100) antibody |
Blocking Peptide |
For anti-NAPA (AVARP13049_T100) antibody is Catalog # AAP30724 (Previous Catalog # AAPP01381) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human NAPA |
Uniprot ID |
P54920 |
Protein Name |
Alpha-soluble NSF attachment protein |
Protein Accession # |
NP_003818 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_003827 |
Gene Symbol |
NAPA |
Predicted Species Reactivity |
Mouse, Cow, Dog, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Mouse: 78%; Zebrafish: 78% |
Image 1 | |
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