SREBF2 Antibody - middle region (AVARP09037_P050)

• Product Number: AVARP09037_P050
• Name: SREBF2 Antibody - middle region (AVARP09037_P050)
• Protein Size (# AA): 1141 amino acids
• Molecular Weight: 124kDa
• NCBI Gene Id: 6721
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Sterol regulatory element binding transcription factor 2
• Alias Symbols: SREBP2, bHLHd2, SREBP-2
• Peptide Sequence: Synthetic peptide located within the following region: PASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRIL
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Zeng,L., et al., (2004) J. Biol. Chem. 279 (47), 48801-48807
• Description of Target: SREBF2 is a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Protein Interactions: UBC; ERLIN2; MRPS6; NAE1; MAPK3; MAPK1; PARK7; SCAP; SREBF2; SREBF1; NPAT; HINFP; TRRAP; SUMO2; RNF139; SMAD3; HNF4A; ATF6; KLF13; LZTR1; ABLIM2; ATF7IP; ZDHHC17; COPS5; OS9; PIAS3; CASP8AP2; ARHGEF1; PIAS2; SLC4A4; PIAS1; ZYX; ZMYM2; UBE2I; TTC1; SPTBN1;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-SREBF2 (AVARP09037_P050) antibody is Catalog # AAP30614 (Previous Catalog # AAPP01267)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SREBF2
• Uniprot ID: Q12772
• Protein Name: Sterol regulatory element-binding protein 2
• Sample Type Confirmation:

  SREBF2 is strongly supported by BioGPS gene expression data to be expressed in Raji

• Protein Accession #: NP_004590
• Purification: Affinity Purified
• Nucleotide Accession #: NM_004599
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: SREBF2
• Predicted Species Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rat: 100%
• Image 1: mouse glomerular endothelial
  
  WB Suggested Anti-SREBF2 Antibody
  Positive Control: Lane 1: 50ug mouse glomerular endothelial lysate
  Primary Antibody Dilution : 1:1000
  Secondary Antibody : Anti-rabbit-HRP
  Secondry Antibody Dilution : 1:5000
  Submitted by: Xiaoxin Wang, UC Denver
• Image 2: Human Raji
  
  WB Suggested Anti-SREBF2 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: Raji cell lysateSREBF2 is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells