| Product Number |
AVARP09033_P050 |
| Product Page |
www.avivasysbio.com/eif2ak2-antibody-c-terminal-region-avarp09033-p050.html |
| Name |
EIF2AK2 Antibody - C-terminal region (AVARP09033_P050) |
| Protein Size (# AA) |
551 amino acids |
| Molecular Weight |
62kDa |
| NCBI Gene Id |
5610 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Eukaryotic translation initiation factor 2-alpha kinase 2 |
| Alias Symbols |
PKR, PRKR, LEUDEN, EIF2AK1, PPP1R83 |
| Peptide Sequence |
Synthetic peptide located within the following region: IISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Alisi,A., et al., (2005) J Cell Physiol. 205(1), 25-31 |
| Description of Target |
EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex. |
| Protein Interactions |
UBC; TRAF6; TRAF5; TRAF2; EGFR; DHX9; STAU2; PRKRA; EIF2AK2; HECW2; TOP1; STAU1; DICER1; DHX30; EBNA1BP2; IGF2BP2; IGF2BP3; PABPC4; MOV10; ILF3; ILF2; HSP90AA1; EIF2A; NOC3L; GNL3; NOP2; HNRNPC; HIST1H1C; ELAVL1; NPM1; IL7R; gag; Jak2; TYK2; JAK1; EIF2S1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EIF2AK2 (AVARP09033_P050) antibody |
| Blocking Peptide |
For anti-EIF2AK2 (AVARP09033_P050) antibody is Catalog # AAP30599 (Previous Catalog # AAPP01252) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2AK2 |
| Uniprot ID |
P19525 |
| Protein Name |
Interferon-induced, double-stranded RNA-activated protein kinase |
| Protein Accession # |
NP_002750 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002759 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EIF2AK2 |
| Predicted Species Reactivity |
Human |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human Stomach
 | WB Suggested Anti-EIF2AK2 Antibody Titration: 0.125ug/ml
Positive Control: Human Stomach |
| | Image 2 | Human kidney
 | Human kidney |
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