| Product Number |
AVARP09019_T100 |
| Product Page |
www.avivasysbio.com/cav1-antibody-n-terminal-region-avarp09019-t100.html |
| Name |
CAV1 Antibody - N-terminal region (AVARP09019_T100) |
| Protein Size (# AA) |
178 amino acids |
| Molecular Weight |
20kDa |
| NCBI Gene Id |
857 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Caveolin 1, caveolae protein, 22kDa |
| Description |
|
| Alias Symbols |
CGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085 |
| Peptide Sequence |
Synthetic peptide located within the following region: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEID |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Wehner,K.A. Am. J. Physiol., Cell Physiol. 290 (5), C1273-C1274 (2006) |
| Description of Target |
The scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. |
| Protein Interactions |
TFRC; ABCC1; UBC; RPA3; ATG5; ATG12; RPA2; RPA1; PTGIS; EGFR; VCP; UFD1L; PTGS2; PTGS1; ESR1; DERL1; VIMP; ATP4A; CAV2; GLIPR2; KDR; PROCR; F2R; BID; NOS3; HSP90AA1; FAS; ACTB; MALL; NF1; LRP6; KCNMA1; BMPR2; BMPR1A; AXIN1; PPP2CA; MCL1; ITPR3; ID1; TENC1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CAV1 (AVARP09019_T100) antibody |
| Blocking Peptide |
For anti-CAV1 (AVARP09019_T100) antibody is Catalog # AAP30144 (Previous Catalog # AAPS08602) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CAV1 |
| Uniprot ID |
Q03135 |
| Protein Name |
Caveolin-1 |
| Protein Accession # |
NP_001744 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001753 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CAV1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100% |
| Image 1 | Human kidney
 | Human kidney |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-CAV1 Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysate |
|
