| Product Number |
AVARP04006_P050 |
| Product Page |
www.avivasysbio.com/e2f1-antibody-c-terminal-region-avarp04006-p050.html |
| Name |
E2F1 Antibody - C-terminal region (AVARP04006_P050) |
| Protein Size (# AA) |
437 amino acids |
| Molecular Weight |
47kDa |
| NCBI Gene Id |
1869 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
E2F transcription factor 1 |
| Alias Symbols |
RBP3, E2F-1, RBAP1, RBBP3 |
| Peptide Sequence |
Synthetic peptide located within the following region: REDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Unoki,M., et al., (2004) Oncogene 23 (46), 7601-7610 |
| Description of Target |
The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
| Protein Interactions |
RB1; SIRT1; KDM2A; LAMTOR5; EP300; KAT2B; VHL; RARA; STAT1; NCOR2; STOML1; RBL1; MAGEA11; SKP2; UHRF2; UBC; GTF2H1; ERCC3; SPT15; TFB1; TBP; NCOA3; CEBPE; PARP1; PRMT2; RBL2; CCNE1; TFDP2; TFDP1; CDKN2A; CEBPD; CDK2; CDK1; NEDD8; MCPH1; DDB2; DDB1; XIAP; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-E2F1 (AVARP04006_P050) antibody |
| Blocking Peptide |
For anti-E2F1 (AVARP04006_P050) antibody is Catalog # AAP30440 (Previous Catalog # AAPP01024) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human E2F1 |
| Uniprot ID |
Q01094 |
| Protein Name |
Transcription factor E2F1 |
| Sample Type Confirmation |
E2F1 is strongly supported by BioGPS gene expression data to be expressed in Daudi |
| Protein Accession # |
NP_005216 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005225 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
E2F1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Daudi
 | WB Suggested Anti-E2F1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Daudi cell lysateE2F1 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells |
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