| Product Number |
AVARP03009_T100 |
| Product Page |
www.avivasysbio.com/cdk7-antibody-c-terminal-region-avarp03009-t100.html |
| Name |
CDK7 Antibody - C-terminal region (AVARP03009_T100) |
| Protein Size (# AA) |
346 amino acids |
| Molecular Weight |
39kDa |
| NCBI Gene Id |
1022 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Cyclin-dependent kinase 7 |
| Alias Symbols |
CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15 |
| Peptide Sequence |
Synthetic peptide located within the following region: NRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Tassan, J.P., et al., (1994) J. Cell Biol. 127:467-478. |
| Description of Target |
Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti |
| Protein Interactions |
UBC; RPA3; RPA2; RPA1; GTF2H4; GTF2H3; GTF2H2; GTF2H1; ERCC5; ERCC3; ERCC2; CDK7; CCNH; ATP2B4; A2M; GTF2H5; SRPK2; SRPK1; MNAT1; TP53; CDK2; CTD; MBP; CDK1; CCNB1; CCNA2; Dlg4; UVSSA; HSP90AA1; HSD17B4; HLA-DQA1; SUPT5H; POLR2A; GTF2E2; GTF2E1; CDK9; APP |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CDK7 (AVARP03009_T100) antibody |
| Blocking Peptide |
For anti-CDK7 (AVARP03009_T100) antibody is Catalog # AAP30134 (Previous Catalog # AAPP00205) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human CDK7 |
| Uniprot ID |
P50613 |
| Protein Name |
Cyclin-dependent kinase 7 |
| Protein Accession # |
NP_001790 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001799 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CDK7 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
| Application |
IHC, WB, IP |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 94%; Guinea Pig: 94%; Horse: 100%; Human: 100%; Mouse: 88%; Pig: 100%; Rat: 88% |
| Image 1 | Human kidney
 | Human kidney |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-CDK7 Antibody Titration: 1ug/ml
Positive Control: Jurkat cell lysate |
|
| Image 3 | Human Intestine
 | Human Intestine |
|
| Image 4 | HEK293 Whole Cell Lysate
 | CDK7 was immunoprecipitated from 2 mg HEK293 Whole Cell Lysate with AVARP03009_T100 with 1:200 dilution. Western blot was performed using AVARP03009_T100 at 1/1000 dilution.
Lane 1: Control IP in HEK293 Whole Cell Lysate.
Lane 2: CDK7 IP with AVARP03009_T100 in HEK293 Whole Cell Lysate.
Lane 3: Input of HEK293 Whole Cell Lysate. |
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