| Product Number |
AVARP01005_P050 |
| Product Page |
www.avivasysbio.com/bcl2-antibody-n-terminal-region-avarp01005-p050.html |
| Name |
BCL2 Antibody - N-terminal region (AVARP01005_P050) |
| Protein Size (# AA) |
239 amino acids |
| Molecular Weight |
26kDa |
| NCBI Gene Id |
596 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
B-cell CLL/lymphoma 2 |
| Alias Symbols |
Bcl-2, PPP1R50 |
| Peptide Sequence |
Synthetic peptide located within the following region: GHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Chen,R., et al., (2004) J. Cell Biol. 166 (2), 193-203 |
| Description of Target |
The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. |
| Protein Interactions |
KEAP1; SQSTM1; BECN1; UBC; TP53BP2; BID; BCL2L1; BCL2; BAX; BAD; ATP2A3; NR4A1; KRAS; PPID; MDM4; BNIP3; BFAR; CDK1; BAG3; RAF1; IKBKG; TP53; PPP3CC; FKBP8; MAPK8; IKBKB; HSP90AA1; HIF1A; CRYAB; CHUK; PML; BRCA1; AMBRA1; ATG12; BIK; CISD2; MEX3D; PPP1CC; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-BCL2 (AVARP01005_P050) antibody |
| Blocking Peptide |
For anti-BCL2 (AVARP01005_P050) antibody is Catalog # AAP30327 (Previous Catalog # AAPP00708) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2 |
| Uniprot ID |
P10415 |
| Protein Name |
Apoptosis regulator Bcl-2 |
| Protein Accession # |
NP_000624 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000633 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
BCL2 |
| Predicted Species Reactivity |
Human |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human Placenta
 | WB Suggested Anti-BCL2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Placenta |
| | Image 2 | Human kidney
 | Human kidney |
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