Product Number |
AVARP00005_P050 |
Product Page |
www.avivasysbio.com/krt15-antibody-c-terminal-region-avarp00005-p050.html |
Name |
KRT15 Antibody - C-terminal region (AVARP00005_P050) |
Protein Size (# AA) |
456 amino acids |
Molecular Weight |
49kDa |
NCBI Gene Id |
3866 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Keratin 15 |
Alias Symbols |
K15, CK15, K1CO |
Peptide Sequence |
Synthetic peptide located within the following region: RSLLEGQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Radoja,N., et al., (2004) Mol. Cell. Biol. 24 (8), 3168-3179 |
Description of Target |
The protein encoded by KRT15 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Protein Interactions |
MBD3; NUP54; AMOTL2; SPG21; WAC; CYTH4; PRPF31; ARFIP2; ZFYVE26; OIP5; HMG20B; ABI2; CEP57; CREB5; HGS; USP2; LMO4; TMSB4X; SMARCE1; RAD51D; PSMB1; PSMA1; PKN1; PIK3R2; NEFL; MOS; LMO2; KRT86; KRT8; KRT6B; KRT6A; KRT5; KRT4; KIFC3; GFAP; TIMM8A; COX5B; CC |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-KRT15 (AVARP00005_P050) antibody |
Blocking Peptide |
For anti-KRT15 (AVARP00005_P050) antibody is Catalog # AAP30450 (Previous Catalog # AAPP34741) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human KRT15 |
Uniprot ID |
P19012 |
Protein Name |
Keratin, type I cytoskeletal 15 |
Publications |
Celis, J. E. et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol. Cell. Proteomics 7, 1795-809 (2008). 18632593 |
Protein Accession # |
NP_002266 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_002275 |
Tested Species Reactivity |
Human |
Gene Symbol |
KRT15 |
Predicted Species Reactivity |
Human, Mouse, Cow |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Human: 100%; Mouse: 86% |
Image 1 | Human Intestine
| WB Suggested Anti-KRT15 Antibody Titration: 4.0-8.0 Positive Control: Human Intestine |
|
Image 2 | Human brain
| WB Suggested Anti-KRT15 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human brain |
|
Image 3 | Human HepG2
| WB Suggested Anti-KRT15 antibody Titration: 1 ug/mL Sample Type: Human HepG2 |
|
Image 4 | Human Hela
| WB Suggested Anti-KRT15 antibody Titration: 1 ug/mL Sample Type: Human Hela |
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