KRT15 Antibody - C-terminal region (AVARP00005_P050)

Data Sheet
 
Product Number AVARP00005_P050
Product Page www.avivasysbio.com/krt15-antibody-c-terminal-region-avarp00005-p050.html
Name KRT15 Antibody - C-terminal region (AVARP00005_P050)
Protein Size (# AA) 456 amino acids
Molecular Weight 49kDa
NCBI Gene Id 3866
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Keratin 15
Alias Symbols K15, CK15, K1CO
Peptide Sequence Synthetic peptide located within the following region: RSLLEGQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Radoja,N., et al., (2004) Mol. Cell. Biol. 24 (8), 3168-3179
Description of Target The protein encoded by KRT15 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions MBD3; NUP54; AMOTL2; SPG21; WAC; CYTH4; PRPF31; ARFIP2; ZFYVE26; OIP5; HMG20B; ABI2; CEP57; CREB5; HGS; USP2; LMO4; TMSB4X; SMARCE1; RAD51D; PSMB1; PSMA1; PKN1; PIK3R2; NEFL; MOS; LMO2; KRT86; KRT8; KRT6B; KRT6A; KRT5; KRT4; KIFC3; GFAP; TIMM8A; COX5B; CC
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-KRT15 (AVARP00005_P050) antibody
Blocking Peptide For anti-KRT15 (AVARP00005_P050) antibody is Catalog # AAP30450 (Previous Catalog # AAPP34741)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human KRT15
Uniprot ID P19012
Protein Name Keratin, type I cytoskeletal 15
Publications

Celis, J. E. et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol. Cell. Proteomics 7, 1795-809 (2008). 18632593

Protein Accession # NP_002266
Purification Affinity Purified
Nucleotide Accession # NM_002275
Tested Species Reactivity Human
Gene Symbol KRT15
Predicted Species Reactivity Human, Mouse, Cow
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Human: 100%; Mouse: 86%
Image 1
Human Intestine
WB Suggested Anti-KRT15 Antibody Titration: 4.0-8.0
Positive Control: Human Intestine
Image 2
Human brain
WB Suggested Anti-KRT15 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain
Image 3
Human HepG2
WB Suggested Anti-KRT15 antibody Titration: 1 ug/mL
Sample Type: Human HepG2
Image 4
Human Hela
WB Suggested Anti-KRT15 antibody Titration: 1 ug/mL
Sample Type: Human Hela
 

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