CHMP4A Antibody - C-terminal region (ARP61976_P050)

Data Sheet
 
Product Number ARP61976_P050
Product Page www.avivasysbio.com/chmp4a-antibody-c-terminal-region-arp61976-p050.html
Name CHMP4A Antibody - C-terminal region (ARP61976_P050)
Protein Size (# AA) 265 amino acids
Molecular Weight 29kDa
NCBI Gene Id 29082
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Charged multivesicular body protein 4A
Alias Symbols SNF7, CHMP4, SHAX2, CHMP4B, SNF7-1, VPS32A, HSPC134, VPS32-1, C14orf123
Peptide Sequence Synthetic peptide located within the following region: ELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQ
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression
Protein Interactions SYT17; EFHD2; CHRAC1; TALDO1; RCN1; RBBP7; RANBP1; IDH1; HSPE1; DCK; ADSS; EGFR; VPS4B; CHMP4B; TTC19; CC2D1A; CHMP5; CHMP4A; VPS4A; STAMBP; CDK13; CHMP4C; gag; CHMP3; PDCD6IP; PPIA; F2R; UBC; CHMP6;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CHMP4A (ARP61976_P050) antibody
Blocking Peptide For anti-CHMP4A (ARP61976_P050) antibody is Catalog # AAP61976 (Previous Catalog # AAPP48314)
Uniprot ID Q14D22
Protein Name Charged multivesicular body protein 4a Ensembl ENSP00000324205
Sample Type Confirmation

CHMP4A is strongly supported by BioGPS gene expression data to be expressed in 721_B

Protein Accession # NP_054888
Purification Affinity Purified
Nucleotide Accession # NM_014169
Tested Species Reactivity Human
Gene Symbol CHMP4A
Predicted Species Reactivity Human, Rat, Cow, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 77%; Human: 100%; Rabbit: 92%; Rat: 85%
Image 1
Human 721_B
WB Suggested Anti-CHMP4A Antibody
Titration: 1.0 ug/ml
Positive Control: 721_B Whole CellCHMP4A is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
 

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