ADD3 Antibody - C-terminal region (ARP59946_P050)

Data Sheet
 
Product Number ARP59946_P050
Product Page www.avivasysbio.com/add3-antibody-c-terminal-region-arp59946-p050.html
Name ADD3 Antibody - C-terminal region (ARP59946_P050)
Protein Size (# AA) 706 amino acids
Molecular Weight 78kDa
NCBI Gene Id 120
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Adducin 3 (gamma)
Alias Symbols ADDL, CPSQ3
Peptide Sequence Synthetic peptide located within the following region: DELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKF
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.
Protein Interactions UBC; RNF2; HDAC8; ATXN1; SUMO1; PRKCA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ADD3 (ARP59946_P050) antibody
Blocking Peptide For anti-ADD3 (ARP59946_P050) antibody is Catalog # AAP59946 (Previous Catalog # AAPP46109)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ADD3
Uniprot ID Q9UEY8
Protein Name Gamma-adducin
Protein Accession # NP_001112
Purification Affinity Purified
Nucleotide Accession # NM_001121
Tested Species Reactivity Human, Mouse
Gene Symbol ADD3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IF, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human THP1
WB Suggested Anti-ADD3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1 cell lysate
Image 2
mouse HEI-OCI auditory
mouse HEI-OCI auditory
 

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