| Product Number |
ARP59424_P050 |
| Product Page |
www.avivasysbio.com/ufd1-antibody-middle-region-arp59424-p050.html |
| Name |
UFD1 Antibody - middle region (ARP59424_P050) |
| Protein Size (# AA) |
307 amino acids |
| Molecular Weight |
34kDa |
| NCBI Gene Id |
7353 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
ubiquitin recognition factor in ER associated degradation 1 |
| Alias Symbols |
UFD1L |
| Peptide Sequence |
Synthetic peptide located within the following region: NYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPERQVQHEEST |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. |
| Protein Interactions |
HUWE1; YOD1; VCP; UBC; SHFM1; SUZ12; BTRC; EZH2; PDCD4; NPLOC4; NFKBIA; NUB1; NEDD8; CAV1; ADRB2; FAF1; TXLNA; UNC45A; VPS33B; UBE3A; UBE2N; PSMD7; SPRTN; UBXN6; GZMK; ERLIN2; ITPR1; PPHLN1; ANAPC2; TIAM2; TAF1C; TP53; SNX1; MASP1; PIK3CA; NGFR; IGHM; F13 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-UFD1 (ARP59424_P050) antibody |
| Blocking Peptide |
For anti-UFD1 (ARP59424_P050) antibody is Catalog # AAP59424 (Previous Catalog # AAPP45525) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human UFD1L |
| Uniprot ID |
Q92890 |
| Protein Name |
ubiquitin recognition factor in ER-associated degradation protein 1 |
| Sample Type Confirmation |
UFD1L is supported by BioGPS gene expression data to be expressed in MCF7 |
| Protein Accession # |
NP_005650 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005659 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
UFD1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79% |
| Image 1 | Human MCF-7
 | WB Suggested Anti-UFD1L Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysateUFD1L is supported by BioGPS gene expression data to be expressed in MCF7 |
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