CD4 Antibody - C-terminal region (ARP59105_P050)

Data Sheet
 
Product Number ARP59105_P050
Product Page www.avivasysbio.com/cd4-antibody-c-terminal-region-arp59105-p050.html
Name CD4 Antibody - C-terminal region (ARP59105_P050)
Protein Size (# AA) 458 amino acids
Molecular Weight 48kDa
NCBI Gene Id 920
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name CD4 molecule
Alias Symbols IMD79, OKT4D, CD4mut
Peptide Sequence Synthetic peptide located within the following region: VLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Protein Interactions env; RANBP9; vpu; ADRB2; UBC; CXCR4; UBL7; ABCB1; INPPL1; VCP; HGS; LCK; NR3C1; STUB1; TUBB; MYL12A; DHRS2; LRPPRC; FARSB; EIF3I; EIF3D; EIF3C; EIF3B; VIM; VDAC3; VDAC2; VDAC1; SSRP1; RPS19; RPS12; RPS10; RPS9; RPLP1; RPLP0; RPL22; RPL18; RPL7; PHB; NPM1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CD4 (ARP59105_P050) antibody
Blocking Peptide For anti-CD4 (ARP59105_P050) antibody is Catalog # AAP59105 (Previous Catalog # AAPP45323)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CD4
Uniprot ID P01730
Protein Name T-cell surface glycoprotein CD4
Protein Accession # NP_000607
Purification Affinity Purified
Nucleotide Accession # NM_000616
Tested Species Reactivity Human
Gene Symbol CD4
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%
Image 1
Human Placenta
WB Suggested Anti-CD4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Placenta
 

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