Product Number |
ARP58924_P050 |
Product Page |
www.avivasysbio.com/atg16l1-antibody-n-terminal-region-arp58924-p050.html |
Name |
ATG16L1 Antibody - N-terminal region (ARP58924_P050) |
Protein Size (# AA) |
523 amino acids |
Molecular Weight |
58kDa |
NCBI Gene Id |
55054 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
ATG16 autophagy related 16-like 1 (S. cerevisiae) |
Alias Symbols |
IBD10, WDR30, APG16L, ATG16A, ATG16L |
Peptide Sequence |
Synthetic peptide located within the following region: EYDALQITFTALEGKLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSR |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy. |
Protein Interactions |
WIPI2; RB1CC1; DEDD2; TRAF3IP3; NOD2; TMEM59; TLR2; SUMO2; ATG13; ATG5; ULK1; UBC; TNK2; SYNPO2; ATG12; NOD1; WDFY3; APP; RAB33B; RAB35; RAB3D; RAB33A; HSPA4; FCGRT; CLTC; AP2M1; ELAVL1; MAP1LC3C; MAP1LC3B; ATG3; CCT2; CCT7; AGPS; GAN; CCT3; SNAPC4; ATG16 |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ATG16L1 (ARP58924_P050) antibody |
Blocking Peptide |
For anti-ATG16L1 (ARP58924_P050) antibody is Catalog # AAP58924 (Previous Catalog # AAPP44871) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ATG16L1 |
Uniprot ID |
Q53SV2 |
Protein Name |
Putative uncharacterized protein FLJ10035 EMBL AAY14860.1 |
Sample Type Confirmation |
ATG16L1 is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_001177195 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001190266 |
Tested Species Reactivity |
Human |
Gene Symbol |
ATG16L1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 86% |
Image 1 | Human Jurkat
| WB Suggested Anti-ATG16L1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateATG16L1 is supported by BioGPS gene expression data to be expressed in Jurkat |
|