| Product Number |
ARP58318_P050 |
| Product Page |
www.avivasysbio.com/pot1-antibody-middle-region-arp58318-p050.html |
| Name |
POT1 Antibody - middle region (ARP58318_P050) |
| Protein Size (# AA) |
634 amino acids |
| Molecular Weight |
71kDa |
| NCBI Gene Id |
25913 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Protection of telomeres 1 homolog (S. pombe) |
| Alias Symbols |
GLM9, CMM10, HPOT1 |
| Peptide Sequence |
Synthetic peptide located within the following region: CPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. |
| Protein Interactions |
TPP1; CFL2; ACD; CORO1A; KHDRBS1; LAMC3; BCAS2; MVP; ZNF32; ECI1; CSNK2B; COX6A2; ALDH1A1; ACTN4; SERTAD1; C2orf74; ZBTB49; ZBED2; CYP4F11; MYO5C; RIF1; NAP1L1; MDM2; KRT18; GRN; PACSIN1; SULT4A1; PGLS; AIPL1; SH3BP1; HAAO; NCDN; TWF2; ACOT7; DDX19B; PACS |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-POT1 (ARP58318_P050) antibody |
| Blocking Peptide |
For anti-POT1 (ARP58318_P050) antibody is Catalog # AAP58318 (Previous Catalog # AAPP33180) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human POT1 |
| Uniprot ID |
Q9NUX5 |
| Protein Name |
Protection of telomeres protein 1 |
| Protein Accession # |
NP_001036059 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001042594 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
POT1 |
| Predicted Species Reactivity |
Human, Rat, Dog, Guinea Pig, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 79%; Guinea Pig: 85%; Horse: 79%; Human: 100%; Rat: 92% |
| Image 1 | Human HeLa
 | WB Suggested Anti-POT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Hela cell lysate |
|
|
