GEMIN4 Antibody - N-terminal region (ARP56757_P050)

Data Sheet
 
Product Number ARP56757_P050
Product Page www.avivasysbio.com/gemin4-antibody-n-terminal-region-arp56757-p050.html
Name GEMIN4 Antibody - N-terminal region (ARP56757_P050)
Protein Size (# AA) 1058 amino acids
Molecular Weight 120kDa
NCBI Gene Id 50628
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Gem (nuclear organelle) associated protein 4
Description
Alias Symbols p97, HC56, HCAP1, HHRF-1, NEDMCR
Peptide Sequence Synthetic peptide located within the following region: QALAEKVKEAERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLR
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Shpargel,K.B. (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (48), 17372-17377
Description of Target The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes requi
Protein Interactions UBC; RPA3; RPA2; RPA1; BMI1; MIB1; RN7SL1; EGFR; GEMIN4; DICER1; DDX20; SMN1; HDAC11; GLYR1; FLAD1; MORC4; vpr; SRRT; AGO2; PNKP; PIAS3; SPRY1; CALCOCO2; IQCB1; SQSTM1; UBL4A; DMPK; GEMIN2; SRP54; SRP9; RNU2-1; BARD1; RNU1-1; GEMIN5; TOP1; GRK5; SIRT7; SU
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-GEMIN4 (ARP56757_P050) antibody
Blocking Peptide For anti-GEMIN4 (ARP56757_P050) antibody is Catalog # AAP56757 (Previous Catalog # AAPP39614)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human GEMIN4
Uniprot ID Q8WUM5
Protein Name Gem (Nuclear organelle) associated protein 4 EMBL AAH20062.1
Publications

CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation. Cell Death Dis. 12, 1040 (2021). 34725334

Sample Type Confirmation

GEMIN4 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_056536
Purification Affinity Purified
Nucleotide Accession # NM_015721
Tested Species Reactivity Human
Gene Symbol GEMIN4
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human Jurkat
WB Suggested Anti-GEMIN4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateGEMIN4 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
 

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