Product Number |
ARP56757_P050 |
Product Page |
www.avivasysbio.com/gemin4-antibody-n-terminal-region-arp56757-p050.html |
Name |
GEMIN4 Antibody - N-terminal region (ARP56757_P050) |
Protein Size (# AA) |
1058 amino acids |
Molecular Weight |
120kDa |
NCBI Gene Id |
50628 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Gem (nuclear organelle) associated protein 4 |
Description |
|
Alias Symbols |
p97, HC56, HCAP1, HHRF-1, NEDMCR |
Peptide Sequence |
Synthetic peptide located within the following region: QALAEKVKEAERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLR |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Shpargel,K.B. (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (48), 17372-17377 |
Description of Target |
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes requi |
Protein Interactions |
UBC; RPA3; RPA2; RPA1; BMI1; MIB1; RN7SL1; EGFR; GEMIN4; DICER1; DDX20; SMN1; HDAC11; GLYR1; FLAD1; MORC4; vpr; SRRT; AGO2; PNKP; PIAS3; SPRY1; CALCOCO2; IQCB1; SQSTM1; UBL4A; DMPK; GEMIN2; SRP54; SRP9; RNU2-1; BARD1; RNU1-1; GEMIN5; TOP1; GRK5; SIRT7; SU |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-GEMIN4 (ARP56757_P050) antibody |
Blocking Peptide |
For anti-GEMIN4 (ARP56757_P050) antibody is Catalog # AAP56757 (Previous Catalog # AAPP39614) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human GEMIN4 |
Uniprot ID |
Q8WUM5 |
Protein Name |
Gem (Nuclear organelle) associated protein 4 EMBL AAH20062.1 |
Publications |
CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation. Cell Death Dis. 12, 1040 (2021). 34725334 |
Sample Type Confirmation |
GEMIN4 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_056536 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_015721 |
Tested Species Reactivity |
Human |
Gene Symbol |
GEMIN4 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human Jurkat
| WB Suggested Anti-GEMIN4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateGEMIN4 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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