| Product Number |
ARP54791_P050 |
| Product Page |
www.avivasysbio.com/sfn-antibody-n-terminal-region-arp54791-p050.html |
| Name |
SFN Antibody - N-terminal region (ARP54791_P050) |
| Protein Size (# AA) |
248 amino acids |
| Molecular Weight |
28kDa |
| NCBI Gene Id |
2810 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Stratifin |
| Alias Symbols |
YWHAS |
| Peptide Sequence |
Synthetic peptide located within the following region: VVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. |
| Protein Interactions |
FAM9B; RAB3IP; LONRF1; CCDC102B; ZC2HC1C; DTL; FAM53C; MKRN3; FOXO4; MAGEA1; CCNH; SIK3; ZFYVE19; YWHAZ; VCL; UBE2V1; SNRPF; UBE2R2; PAK2; G6PD; TARDBP; EGFR; BAD; MARK3; HDAC7; HDAC5; HDAC4; RAF1; CDC25C; MST1R; ABL1; HNRNPD; ATF2; TRIM32; COPS6; UBC; TP |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SFN (ARP54791_P050) antibody |
| Blocking Peptide |
For anti-SFN (ARP54791_P050) antibody is Catalog # AAP54791 (Previous Catalog # AAPP44533) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SFN |
| Uniprot ID |
P31947 |
| Protein Name |
14-3-3 protein sigma |
| Protein Accession # |
NP_006133 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006142 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SFN |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93% |
| Image 1 | Human Placenta
 | WB Suggested Anti-SFN Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Placenta |
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