Product Number |
ARP52865_P050 |
Product Page |
www.avivasysbio.com/fbxo32-antibody-n-terminal-region-arp52865-p050.html |
Name |
FBXO32 Antibody - N-terminal region (ARP52865_P050) |
Protein Size (# AA) |
355 amino acids |
Molecular Weight |
42 kDa |
NCBI Gene Id |
114907 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
F-box protein 32 |
Alias Symbols |
Fbx32, MAFbx |
Peptide Sequence |
Synthetic peptide located within the following region: QQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSDGRDLVSLGQAAPDL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes. |
Protein Interactions |
UBC; MLH1; Mutyh; UBE2D3; KHDRBS3; SERPINB5; CDC34; DUSP1; FBXO25; MYBPC3; CDKN1A; EIF3F; SKP1; EIF3A; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
|
Datasheets/Manuals |
Printable datasheet for anti-FBXO32 (ARP52865_P050) antibody |
Blocking Peptide |
For anti-FBXO32 (ARP52865_P050) antibody is Catalog # AAP52865 (Previous Catalog # AAPP33923) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO32 |
Uniprot ID |
Q0VAQ6 |
Protein Name |
F-box protein 32 EMBL AAI20965.1 |
Protein Accession # |
NP_680482 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_148177 |
Tested Species Reactivity |
Human |
Gene Symbol |
FBXO32 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
Image 1 | 25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
| 25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. |
|
|