| Product Number |
ARP51872_P050 |
| Product Page |
www.avivasysbio.com/sfrs12-antibody-n-terminal-region-arp51872-p050.html |
| Name |
SFRS12 Antibody - N-terminal region (ARP51872_P050) |
| Protein Size (# AA) |
624 amino acids |
| Molecular Weight |
72kDa |
| NCBI Gene Id |
140890 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Splicing regulatory glutamine/lysine-rich protein 1 |
| Alias Symbols |
SFRS12, SRrp86, SRrp508 |
| Peptide Sequence |
Synthetic peptide located within the following region: DPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEESKALSLLAPAPTMTSL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007) |
| Description of Target |
SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins.SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002 [PubMed 11991645]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-78 AW963850.1 1-78 79-415 AK091758.1 1-337 416-2238 BC067770.1 609-2431 2239-3654 BC112343.1 1800-3215 3655-3660 AK125893.1 3379-3384 3661-4030 AL049309.1 705-1074 |
| Protein Interactions |
SREK1; SRSF11; LIN28A; SRPK2; SRPK1; MDM2; VPS33A; CUL1; ELAVL1; HNRNPA1; DDX3X; CSNK2B; C1QBP; PARP1; HNRNPCL1; HNRNPA3; NFATC2IP; SH3GLB2; RBMX; PABPC1; SRPK3; SF3B3; SUPT16H; SF3A3; SRSF8; SRSF10; DDX17; GNB2L1; THRAP3; ZRANB2; EFTUD2; PABPC4; SRSF9; D |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SREK1 (ARP51872_P050) antibody |
| Blocking Peptide |
For anti-SREK1 (ARP51872_P050) antibody is Catalog # AAP51872 (Previous Catalog # AAPP40051) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS12 |
| Uniprot ID |
Q8WXA9-2 |
| Protein Name |
Splicing regulatory glutamine/lysine-rich protein 1 |
| Sample Type Confirmation |
SREK1 is supported by BioGPS gene expression data to be expressed in HT1080 |
| Protein Accession # |
NP_001070667 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001077199 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SREK1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human HT1080
 | WB Suggested Anti-SFRS12 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HT1080 cell lysateSREK1 is supported by BioGPS gene expression data to be expressed in HT1080 |
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