PAXIP1 Antibody - N-terminal region (ARP51642_P050)

Data Sheet
 
Product Number ARP51642_P050
Product Page www.avivasysbio.com/paxip1-antibody-n-terminal-region-arp51642-p050.html
Name PAXIP1 Antibody - N-terminal region (ARP51642_P050)
Protein Size (# AA) 697 amino acids
Molecular Weight 74kDa
NCBI Gene Id 22976
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name PAX interacting (with transcription-activation domain) protein 1
Alias Symbols PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L
Peptide Sequence Synthetic peptide located within the following region: MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVP
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
Protein Interactions MAPRE2; POM121; NXT1; PPARG; XAGE1E; SMAD2; SPATA18; COMTD1; BTBD16; DIS3L; LACTB; HNRNPLL; ZNF251; ZNF622; BTBD6; C7orf50; FAM175A; TMEM120A; FAHD1; TM2D3; ATHL1; CENPU; DYNC2H1; BRCC3; KRI1; ANAPC1; NOM1; POLR1E; NCAPG; AASDHPPT; RBM25; CATSPERG; WDR48;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for ARP51642_P050
Blocking Peptide Catalog # AAP51642 (Previous Catalog # AAPP30059)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
Uniprot ID Q6ZW49
Protein Name PAX-interacting protein 1
Sample Type Confirmation

PAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B

Protein Accession # EAX04525
Purification Affinity Purified
Nucleotide Accession # NM_007349
Tested Species Reactivity Human
Gene Symbol PAXIP1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Image 1
Human 721_B
WB Suggested Anti-PAXIP1 Antibody Titration: 0.2-1 ug/ml
Positive Control: 721_B cell lysatePAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B
 

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