Product Number |
ARP51642_P050 |
Product Page |
www.avivasysbio.com/paxip1-antibody-n-terminal-region-arp51642-p050.html |
Name |
PAXIP1 Antibody - N-terminal region (ARP51642_P050) |
Protein Size (# AA) |
697 amino acids |
Molecular Weight |
74kDa |
NCBI Gene Id |
22976 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
PAX interacting (with transcription-activation domain) protein 1 |
Alias Symbols |
PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L |
Peptide Sequence |
Synthetic peptide located within the following region: MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVP |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation. |
Protein Interactions |
MAPRE2; POM121; NXT1; PPARG; XAGE1E; SMAD2; SPATA18; COMTD1; BTBD16; DIS3L; LACTB; HNRNPLL; ZNF251; ZNF622; BTBD6; C7orf50; FAM175A; TMEM120A; FAHD1; TM2D3; ATHL1; CENPU; DYNC2H1; BRCC3; KRI1; ANAPC1; NOM1; POLR1E; NCAPG; AASDHPPT; RBM25; CATSPERG; WDR48; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for ARP51642_P050 |
Blocking Peptide |
Catalog # AAP51642 (Previous Catalog # AAPP30059) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1 |
Uniprot ID |
Q6ZW49 |
Protein Name |
PAX-interacting protein 1 |
Sample Type Confirmation |
PAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B |
Protein Accession # |
EAX04525 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_007349 |
Tested Species Reactivity |
Human |
Gene Symbol |
PAXIP1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79% |
Image 1 | Human 721_B
| WB Suggested Anti-PAXIP1 Antibody Titration: 0.2-1 ug/ml Positive Control: 721_B cell lysatePAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B |
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