RBBP8 Antibody - middle region (ARP50888_P050)

Data Sheet
 
Product Number ARP50888_P050
Product Page www.avivasysbio.com/rbbp8-antibody-middle-region-arp50888-p050.html
Name RBBP8 Antibody - middle region (ARP50888_P050)
Protein Size (# AA) 867 amino acids
Molecular Weight 98kDa
NCBI Gene Id 5932
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Retinoblastoma binding protein 8
Alias Symbols RIM, COM1, CTIP, JWDS, SAE2, SCKL2
Peptide Sequence Synthetic peptide located within the following region: CQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Protein Interactions LMO4; PIN1; LMO1; MDM2; BRCA1; RBL1; TMEM54; PRRG4; RGS17; IKBKG; IGFBP7; EEF1A1; CTBP2; CLU; MAP2K4; RAF1; RBL2; PCNA; ZNF350; NBN; UIMC1; PALB2; BARD1; SPEN; RAD50; CTBP1; RB1; UBC; FXR2; RBBP8; IKZF1; LIMS1; SIAH2; SIAH1; LMO2; WDYHV1; ATM; TGIF2; IKZF
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for ARP50888_P050
Blocking Peptide Catalog # AAP50888 (Previous Catalog # AAPs30412)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human RBBP8
Uniprot ID A6NKN2
Protein Name DNA endonuclease RBBP8 Ensembl ENSP00000382630
Sample Type Confirmation

RBBP8 is supported by BioGPS gene expression data to be expressed in ACHN

Protein Accession # NP_976037
Purification Affinity Purified
Nucleotide Accession # NM_203292
Tested Species Reactivity Human
Gene Symbol RBBP8
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Human: 100%
Image 1
Human ACHN
WB Suggested Anti-RBBP8 Antibody Titration: 0.2-1 ug/ml
Positive Control: ACHN cell lysateRBBP8 is supported by BioGPS gene expression data to be expressed in ACHN
 

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