Product Number |
ARP50888_P050 |
Product Page |
www.avivasysbio.com/rbbp8-antibody-middle-region-arp50888-p050.html |
Name |
RBBP8 Antibody - middle region (ARP50888_P050) |
Protein Size (# AA) |
867 amino acids |
Molecular Weight |
98kDa |
NCBI Gene Id |
5932 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Retinoblastoma binding protein 8 |
Alias Symbols |
RIM, COM1, CTIP, JWDS, SAE2, SCKL2 |
Peptide Sequence |
Synthetic peptide located within the following region: CQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. |
Protein Interactions |
LMO4; PIN1; LMO1; MDM2; BRCA1; RBL1; TMEM54; PRRG4; RGS17; IKBKG; IGFBP7; EEF1A1; CTBP2; CLU; MAP2K4; RAF1; RBL2; PCNA; ZNF350; NBN; UIMC1; PALB2; BARD1; SPEN; RAD50; CTBP1; RB1; UBC; FXR2; RBBP8; IKZF1; LIMS1; SIAH2; SIAH1; LMO2; WDYHV1; ATM; TGIF2; IKZF |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for ARP50888_P050 |
Blocking Peptide |
Catalog # AAP50888 (Previous Catalog # AAPs30412) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human RBBP8 |
Uniprot ID |
A6NKN2 |
Protein Name |
DNA endonuclease RBBP8 Ensembl ENSP00000382630 |
Sample Type Confirmation |
RBBP8 is supported by BioGPS gene expression data to be expressed in ACHN |
Protein Accession # |
NP_976037 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_203292 |
Tested Species Reactivity |
Human |
Gene Symbol |
RBBP8 |
Predicted Species Reactivity |
Human |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100% |
Image 1 | Human ACHN
| WB Suggested Anti-RBBP8 Antibody Titration: 0.2-1 ug/ml Positive Control: ACHN cell lysateRBBP8 is supported by BioGPS gene expression data to be expressed in ACHN |
|
|