| Product Number |
ARP50568_P050 |
| Product Page |
www.avivasysbio.com/trappc2-antibody-middle-region-arp50568-p050.html |
| Name |
TRAPPC2 Antibody - middle region (ARP50568_P050) |
| Protein Size (# AA) |
140 amino acids |
| Molecular Weight |
16kDa |
| Subunit |
2 |
| NCBI Gene Id |
6399 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Trafficking protein particle complex 2 |
| Alias Symbols |
SEDL, SEDT, MIP2A, TRS20, ZNF547L, hYP38334, TRAPPC2P1 |
| Peptide Sequence |
Synthetic peptide located within the following region: RQEDGIKNFFTDVYDLYIKFSMNPFYEPNSPIRSSAFDRKVQFLGKKHLL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ross,M.T., (2005) Nature 434 (7031), 325-337 |
| Description of Target |
TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene. |
| Protein Interactions |
TRAPPC3L; TRAPPC5; TRAPPC6B; TRAPPC9; TRAPPC6A; TRAPPC11; TRAPPC4; TRAPPC12; TRAPPC3; TRAPPC8; TRAPPC10; ELAVL1; UBC; JOSD2; CLIC1; CLIC2; ENO1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for ARP50568_P050 |
| Blocking Peptide |
Catalog # AAP50568 (Previous Catalog # AAPP13941) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TRAPPC2 |
| Uniprot ID |
O14582 |
| Protein Accession # |
NP_055378 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_014563 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TRAPPC2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100% |
| Image 1 | Human Spleen
 | WB Suggested Anti-TRAPPC2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human Spleen |
|
