| Product Number |
ARP48923_P050 |
| Product Page |
www.avivasysbio.com/tgs1-antibody-middle-region-arp48923-p050.html |
| Name |
TGS1 Antibody - middle region (ARP48923_P050) |
| Protein Size (# AA) |
853 amino acids |
| Molecular Weight |
96kDa |
| NCBI Gene Id |
96764 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Trimethylguanosine synthase 1 |
| Alias Symbols |
PIMT, PIPMT, NCOA6IP |
| Peptide Sequence |
Synthetic peptide located within the following region: IDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKY |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Fanelus,I. (2008) Biochem. Biophys. Res. Commun. 371 (2), 203-208 |
| Description of Target |
TGS1 catalyzes the methylation step(s) for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. TGS1 plays a role in transcriptional regulation. |
| Protein Interactions |
LIN28A; UBC; COIL; Nhp2l1; NCOA6; HNF4A; EP300; EED; CREBBP; SNORD3A; MED1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TGS1 (ARP48923_P050) antibody |
| Blocking Peptide |
For anti-TGS1 (ARP48923_P050) antibody is Catalog # AAP48923 (Previous Catalog # AAPP28973) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TGS1 |
| Uniprot ID |
Q96RS0 |
| Protein Name |
Trimethylguanosine synthase |
| Protein Accession # |
NP_079107 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_024831 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TGS1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-TGS1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate |
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