TMPRSS11D Antibody - N-terminal region (ARP46418_T100)

Data Sheet
 
Product Number ARP46418_T100
Product Page www.avivasysbio.com/tmprss11d-antibody-n-terminal-region-arp46418-t100.html
Name TMPRSS11D Antibody - N-terminal region (ARP46418_T100)
Protein Size (# AA) 418 amino acids
Molecular Weight 46kDa
NCBI Gene Id 9407
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Transmembrane protease, serine 11D
Alias Symbols ASP, HAT
Peptide Sequence Synthetic peptide located within the following region: RSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Matsushima,R., Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2), L385-L395 (2006)
Description of Target TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TMPRSS11D (ARP46418_T100) antibody
Additional Information IHC Information: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.
Blocking Peptide For anti-TMPRSS11D (ARP46418_T100) antibody is Catalog # AAP46418 (Previous Catalog # AAPS18108)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D
Uniprot ID O60235
Protein Name Transmembrane protease serine 11D
Protein Accession # NP_004253
Purification Protein A purified
Nucleotide Accession # NM_004262
Tested Species Reactivity Human
Gene Symbol TMPRSS11D
Predicted Species Reactivity Human, Guinea Pig, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Guinea Pig: 79%; Horse: 79%; Human: 100%; Rabbit: 79%
Image 1
Human HepG2
WB Suggested Antibody Titration: 2.5 ug/ml
Positive Control: HepG2
Image 2
Human Lung
Human Lung
 

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