Product Number |
ARP46070_T100 |
Product Page |
www.avivasysbio.com/ctps-antibody-c-terminal-region-arp46070-t100.html |
Name |
CTPS Antibody - C-terminal region (ARP46070_T100) |
Protein Size (# AA) |
591 amino acids |
Molecular Weight |
67kDa |
NCBI Gene Id |
1503 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
CTP synthase |
Alias Symbols |
CTPS, GATD5, IMD24 |
Peptide Sequence |
Synthetic peptide located within the following region: FGLLLASVGRLSHYLQKGCRLSPRDTYSDRSGSSSPDSEITELKFPSINH |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Han,G.S., (2005) J. Biol. Chem. 280 (46), 38328-38336 |
Description of Target |
The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types. |
Protein Interactions |
UBC; CTPS1; TUBGCP3; AURKA; SUMO2; SUMO3; SUMO1; NEDD8; DCTPP1; GINS3; UBA6; UBXN1; PAPSS1; VCL; UBA1; PPP5C; PKM; DFFA; CS; CLNS1A; ACO1; YWHAQ; MYC; RBM28; POLR1C; FBXO6; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4B; CUL5; CDK2; ARRB2; RAD21; PSMA3; YWHAG; TRA |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CTPS1 (ARP46070_T100) antibody |
Blocking Peptide |
For anti-CTPS1 (ARP46070_T100) antibody is Catalog # AAP46070 (Previous Catalog # AAPS17304) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human CTPS |
Uniprot ID |
P17812 |
Protein Name |
CTP synthase 1 |
Protein Accession # |
NP_001896 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001905 |
Tested Species Reactivity |
Human |
Gene Symbol |
CTPS1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
Image 1 | Human HepG2
| WB Suggested Anti-CTPS Antibody Titration: 5.0ug/ml Positive Control: HepG2 cell lysate |
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