CTPS Antibody - C-terminal region (ARP46070_T100)

Data Sheet
 
Product Number ARP46070_T100
Product Page www.avivasysbio.com/ctps-antibody-c-terminal-region-arp46070-t100.html
Name CTPS Antibody - C-terminal region (ARP46070_T100)
Protein Size (# AA) 591 amino acids
Molecular Weight 67kDa
NCBI Gene Id 1503
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name CTP synthase
Alias Symbols CTPS, GATD5, IMD24
Peptide Sequence Synthetic peptide located within the following region: FGLLLASVGRLSHYLQKGCRLSPRDTYSDRSGSSSPDSEITELKFPSINH
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Han,G.S., (2005) J. Biol. Chem. 280 (46), 38328-38336
Description of Target The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.
Protein Interactions UBC; CTPS1; TUBGCP3; AURKA; SUMO2; SUMO3; SUMO1; NEDD8; DCTPP1; GINS3; UBA6; UBXN1; PAPSS1; VCL; UBA1; PPP5C; PKM; DFFA; CS; CLNS1A; ACO1; YWHAQ; MYC; RBM28; POLR1C; FBXO6; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4B; CUL5; CDK2; ARRB2; RAD21; PSMA3; YWHAG; TRA
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CTPS1 (ARP46070_T100) antibody
Blocking Peptide For anti-CTPS1 (ARP46070_T100) antibody is Catalog # AAP46070 (Previous Catalog # AAPS17304)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CTPS
Uniprot ID P17812
Protein Name CTP synthase 1
Protein Accession # NP_001896
Purification Protein A purified
Nucleotide Accession # NM_001905
Tested Species Reactivity Human
Gene Symbol CTPS1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Image 1
Human HepG2
WB Suggested Anti-CTPS Antibody Titration: 5.0ug/ml
Positive Control: HepG2 cell lysate
 

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