SNF1LK Antibody - N-terminal region (ARP45918_T100)

Data Sheet
 
Product Number ARP45918_T100
Product Page www.avivasysbio.com/snf1lk-antibody-n-terminal-region-arp45918-t100.html
Name SNF1LK Antibody - N-terminal region (ARP45918_T100)
Protein Size (# AA) 783 amino acids
Molecular Weight 85 kDa
NCBI Gene Id 150094
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Salt-inducible kinase 1
Alias Symbols MSK, SIK, DEE30, SIK-1, SIK1B, SNF1LK
Peptide Sequence Synthetic peptide located within the following region: MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Nishimura,Y., (1999) Biochem. Biophys. Res. Commun. 254 (1), 21-26
Description of Target SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
Protein Interactions TAB2; MAP3K7; HDAC5; UBC; SUPT5H; RPL3; PRKACA; NMNAT1; STK11; ELAVL1; YWHAZ; PRKAA1; CRTC2; VAPA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-SIK1 (ARP45918_T100) antibody
Additional Information IHC Information: Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.
Blocking Peptide For anti-SIK1 (ARP45918_T100) antibody is Catalog # AAP45918 (Previous Catalog # AAPS17111)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SNF1LK
Uniprot ID P57059
Protein Name Serine/threonine-protein kinase SIK1
Protein Accession # NP_775490
Purification Protein A purified
Nucleotide Accession # NM_173354
Tested Species Reactivity Human
Gene Symbol SIK1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 90%; Rat: 100%
Image 1
Human Stomach
Human Stomach
Image 2
Western Blot
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Protein is phosphorylated.
 

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