Product Number |
ARP45918_T100 |
Product Page |
www.avivasysbio.com/snf1lk-antibody-n-terminal-region-arp45918-t100.html |
Name |
SNF1LK Antibody - N-terminal region (ARP45918_T100) |
Protein Size (# AA) |
783 amino acids |
Molecular Weight |
85 kDa |
NCBI Gene Id |
150094 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Salt-inducible kinase 1 |
Alias Symbols |
MSK, SIK, DEE30, SIK-1, SIK1B, SNF1LK |
Peptide Sequence |
Synthetic peptide located within the following region: MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Nishimura,Y., (1999) Biochem. Biophys. Res. Commun. 254 (1), 21-26 |
Description of Target |
SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3. |
Protein Interactions |
TAB2; MAP3K7; HDAC5; UBC; SUPT5H; RPL3; PRKACA; NMNAT1; STK11; ELAVL1; YWHAZ; PRKAA1; CRTC2; VAPA; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-SIK1 (ARP45918_T100) antibody |
Additional Information |
IHC Information: Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%. |
Blocking Peptide |
For anti-SIK1 (ARP45918_T100) antibody is Catalog # AAP45918 (Previous Catalog # AAPS17111) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SNF1LK |
Uniprot ID |
P57059 |
Protein Name |
Serine/threonine-protein kinase SIK1 |
Protein Accession # |
NP_775490 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_173354 |
Tested Species Reactivity |
Human |
Gene Symbol |
SIK1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 90%; Rat: 100% |
Image 1 | Human Stomach
| Human Stomach |
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Image 2 | Western Blot
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Protein is phosphorylated. |
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