RRP1 Antibody - C-terminal region (ARP45812_P050)

• Product Number: ARP45812_P050
• Name: RRP1 Antibody - C-terminal region (ARP45812_P050)
• Protein Size (# AA): 461 amino acids
• Molecular Weight: 53kDa
• NCBI Gene Id: 8568
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Ribosomal RNA processing 1 homolog (S. cerevisiae)
• Alias Symbols: NNP-1, NOP52, RRP1A, D21S2056E
• Peptide Sequence: Synthetic peptide located within the following region: IPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRR
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Behrends,U., (2002) Int. J. Cancer 100 (6), 669-677
• Description of Target: RRP1 is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.
• Protein Interactions: UBC; RNF2; PAN2; WHSC1; BARD1; SIRT7;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-RRP1 (ARP45812_P050) antibody is Catalog # AAP45812 (Previous Catalog # AAPP26752)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RRP1
• Uniprot ID: P56182
• Protein Name: Ribosomal RNA processing protein 1 homolog A
• Publications:

  Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828

• Sample Type Confirmation:

  RRP1 is supported by BioGPS gene expression data to be expressed in HepG2

• Protein Accession #: NP_003674
• Purification: Affinity Purified
• Nucleotide Accession #: NM_003683
• Tested Species Reactivity: Human
• Gene Symbol: RRP1
• Predicted Species Reactivity: Human
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Image 1: Human kidney
  
  Human kidney
• Image 2: Human HepG2
  
  WB Suggested Anti-RRP1 Antibody Titration: 0.2-1 ug/ml
  Positive Control: HepG2 cell lysateRRP1 is supported by BioGPS gene expression data to be expressed in HepG2
• Image 3: Human, Mouse
  
  WB Suggested Anti-RRP1 Antibody Titration: 5% Milk
  ELISA Titer: dilution: 1:500
  Positive Control: human LCL and mouse brains