ECHS1 Antibody - middle region (ARP45699_T100)

Data Sheet
 
Product Number ARP45699_T100
Product Page www.avivasysbio.com/echs1-antibody-middle-region-arp45699-t100.html
Name ECHS1 Antibody - middle region (ARP45699_T100)
Protein Size (# AA) 290 amino acids
Molecular Weight 28kDa
NCBI Gene Id 1892
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Enoyl CoA hydratase, short chain, 1, mitochondrial
Alias Symbols SCEH, ECHS1D
Peptide Sequence Synthetic peptide located within the following region: RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Bruneel,A., (2005) Proteomics 5 (15), 3876-3884
Description of Target ECHS1 functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. ECHS1 is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix.The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.
Protein Interactions SUMO2; UBC; MDM2; GINS3; SMEK2; CNDP2; DCPS; ABHD14A; YWHAQ; SLC9A3R1; USP14; YWHAZ; VCL; UBE2V1; TGM2; RAP1GDS1; PFAS; HSPA9; GSS; CAPN1; CLDN12; UBA1; PPM1B; SERPINA1; ECHS1; CYP2E1; GRB2; UCHL5; UBA5; DDA1; CBWD2; EPB41;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ECHS1 (ARP45699_T100) antibody
Blocking Peptide For anti-ECHS1 (ARP45699_T100) antibody is Catalog # AAP45699 (Previous Catalog # AAPP26694)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human ECHS1
Uniprot ID P30084
Protein Name Enoyl-CoA hydratase, mitochondrial
Protein Accession # NP_004083
Purification Protein A purified
Nucleotide Accession # NM_004092
Tested Species Reactivity Human
Gene Symbol ECHS1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
Image 1
Human Liver
WB Suggested Anti-ECHS1 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: Human Liver
 

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