Product Number |
ARP45690_T100 |
Product Page |
www.avivasysbio.com/cps1-antibody-middle-region-arp45690-t100.html |
Name |
CPS1 Antibody - middle region (ARP45690_T100) |
Protein Size (# AA) |
1500 amino acids |
Molecular Weight |
165kDa |
NCBI Gene Id |
1373 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Carbamoyl-phosphate synthase 1, mitochondrial |
Alias Symbols |
PHN, CPSASE1 |
Peptide Sequence |
Synthetic peptide located within the following region: YPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Huo,R., (2005) J. Biochem. Mol. Biol. 38 (1), 28-33 |
Description of Target |
Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD; MIM 114010), which has been mapped to 2p21.[supplied by OMIM]. |
Protein Interactions |
AGO2; ASB1; FBXO6; UBC; MRPS26; LRPPRC; TOMM70A; SEC22B; PCBP1; HSPA9; HSPA1A; FH; CPT1A; MYC; ELAVL1; SUMO2; RAD21; Csnk1e; Cdk1; RICTOR; YWHAQ; H2AFX; ARAF; RAF1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CPS1 (ARP45690_T100) antibody |
Additional Information |
IHC Information: Fetal liver cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 8%. |
Blocking Peptide |
For anti-CPS1 (ARP45690_T100) antibody is Catalog # AAP45690 (Previous Catalog # AAPP11823) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human CPS1 |
Uniprot ID |
P31327 |
Protein Name |
Carbamoyl-phosphate synthase [ammonia], mitochondrial |
Protein Accession # |
NP_001866 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001875 |
Tested Species Reactivity |
Human, Pig |
Gene Symbol |
CPS1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%; Yeast: 77% |
Image 1 | Human Fetal liver
| WB Suggested Anti-CPS1 Antibody Titration: 5.0ug/ml Positive Control: Fetal liver cell lysate |
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Image 2 | Human Intestine
| Human Intestine |
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Image 3 | Pig duodenum
| Sample Type: Pig duodenum Primary Antibody Dilution: 1:500Secondary Antibody: Anti-rabbit-biotin, streptavidin-HRP Secondary Antibody Dilution: 1:500Color/Signal Descriptions: Brown: CPSGene Name: CPS1Submitted by: Juan C. Mari, USDA/ARS Children's Nutrition Research Center Baylor College of Medicine |
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Image 4 | Pig ileum
| Sample Type: Pig ileum Primary Antibody Dilution: 1:500Secondary Antibody: Anti-rabbit-biotin, streptavidin-HRP Secondary Antibody Dilution: 1:500Color/Signal Descriptions: Brown: CPSGene Name: CPS1Submitted by: Juan C. Mari, USDA/ARS Children's Nutrition Research Center Baylor College of Medicine |
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Image 5 | Pig kidney
| Sample Type: Pig kidney Primary Antibody Dilution: 1:500Secondary Antibody: Anti-rabbit-biotin, streptavidin-HRP Secondary Antibody Dilution: 1:500Color/Signal Descriptions: Brown: CPSGene Name: CPS1Submitted by: Juan C. Mari, USDA/ARS Children's Nutrition Research Center Baylor College of Medicine |
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