| Product Number |
ARP45680_P050 |
| Product Page |
www.avivasysbio.com/kng1-antibody-middle-region-arp45680-p050.html |
| Name |
KNG1 Antibody - middle region (ARP45680_P050) |
| Protein Size (# AA) |
644 amino acids |
| Molecular Weight |
72kDa |
| NCBI Gene Id |
3827 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Kininogen 1 |
| Alias Symbols |
BK, BDK, KNG, HMWK |
| Peptide Sequence |
Synthetic peptide located within the following region: YPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc. |
| Protein Interactions |
Ance; ECE1; COPS6; RXFP4; CPN1; F11; HABP2; CTSK; PREP; MEP1A; ITGB2; GP1BA; KLKB1; KNG1; VTN; THBS1; F2; PLAUR; PLG; KLK1; KRT1; FTL; ELANE; CD93; CTSL; CTSS; CTSG; CAPN2; CAPN1; AGT; APP; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KNG1 (ARP45680_P050) antibody |
| Blocking Peptide |
For anti-KNG1 (ARP45680_P050) antibody is Catalog # AAP45680 (Previous Catalog # AAPP11813) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human KNG1 |
| Uniprot ID |
P01042 |
| Protein Name |
Kininogen-1 |
| Publications |
Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 |
| Protein Accession # |
NP_001095886 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001102416 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KNG1 |
| Predicted Species Reactivity |
Human, Mouse, Horse, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Horse: 85%; Human: 100%; Mouse: 77%; Pig: 92% |
| Image 1 | Human Liver
 | WB Suggested Anti-KNG1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver |
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