| Product Number |
ARP45633_T100 |
| Product Page |
www.avivasysbio.com/nr1h2-antibody-middle-region-arp45633-t100.html |
| Name |
NR1H2 Antibody - middle region (ARP45633_T100) |
| Protein Size (# AA) |
461 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
7376 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 1, group H, member 2 |
| Alias Symbols |
NER, UNR, LXRB, LXR-b, NER-I, RIP15 |
| Peptide Sequence |
Synthetic peptide located within the following region: MIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAI |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Albers,M., (2006) J. Biol. Chem. 281 (8), 4920-4930 |
| Description of Target |
The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995).[supplied by OMIM]. |
| Protein Interactions |
RXRG; MDFI; KDM1A; SUV39H1; ACVRL1; LAMC3; NCOR2; YY1; NPY; CDKN1A; PPARGC1B; PDCD4; PIAS1; USP7; PRKCA; SENP3; CORO2A; MPP1; COL4A5; CHD3; RMI1; CSAD; DUSP12; C14orf1; FAF1; SPRY2; HMGXB4; SORBS2; BAG6; VIM; UBE2D1; SMPD1; ROBO2; NCOR1; NRIP1; NCOA3; VDR |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR1H2 (ARP45633_T100) antibody |
| Blocking Peptide |
For anti-NR1H2 (ARP45633_T100) antibody is Catalog # AAP45633 (Previous Catalog # AAPP11916) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human NR1H2 |
| Uniprot ID |
P55055 |
| Protein Name |
Oxysterols receptor LXR-beta |
| Protein Accession # |
NP_009052 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_007121 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR1H2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-NR1H2 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate |
|
