| Product Number |
ARP45631_P050 |
| Product Page |
www.avivasysbio.com/rxrg-antibody-n-terminal-region-arp45631-p050.html |
| Name |
RXRG Antibody - N-terminal region (ARP45631_P050) |
| Protein Size (# AA) |
463 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
6258 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Retinoid X receptor, gamma |
| Alias Symbols |
RXRC, NR2B3 |
| Peptide Sequence |
Synthetic peptide located within the following region: NVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKH |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Bungard,C.I. Arch. Biochem. Biophys. 443 (1-2), 53-59 (2005) |
| Description of Target |
RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Protein Interactions |
NR1H3; NR1H2; RARB; RARA; MPPED2; UBC; CUL1; DCK; NR1H4; NCOR2; NR1I2; VDR; THRB; RARG; PPARD; MAP4; CAMK2B; CEBPZ; HOXD4; AJUBA; RPAP2; LRSAM1; PNO1; CHGB; THRA; NCOA6; PPARG; SRF; CREBBP; PPARA; NR4A1; Nr0b2; ITGB3BP; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RXRG (ARP45631_P050) antibody |
| Blocking Peptide |
For anti-RXRG (ARP45631_P050) antibody is Catalog # AAP45631 (Previous Catalog # AAPP11914) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RXRG |
| Uniprot ID |
P48443 |
| Protein Name |
Retinoic acid receptor RXR-gamma |
| Protein Accession # |
NP_008848 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006917 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RXRG |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-RXRG Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate |
|
