FMO3 Antibody - N-terminal region (ARP44434_P050)

Data Sheet
 
Product Number ARP44434_P050
Product Page www.avivasysbio.com/fmo3-antibody-n-terminal-region-arp44434-p050.html
Name FMO3 Antibody - N-terminal region (ARP44434_P050)
Protein Size (# AA) 532 amino acids
Molecular Weight 59kDa
NCBI Gene Id 2328
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Flavin containing monooxygenase 3
Description
Alias Symbols TMAU, FMOII, dJ127D3.1
Peptide Sequence Synthetic peptide located within the following region: FMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFATTGQWDVTTE
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Zhang,J. (2006) Drug Metab. Dispos. 34 (1), 19-26
Description of Target FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It acts on TMA to produce TMA-N-oxide.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-FMO3 (ARP44434_P050) antibody
Blocking Peptide For anti-FMO3 (ARP44434_P050) antibody is Catalog # AAP44434 (Previous Catalog # AAPP25744)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human FMO3
Uniprot ID P31513
Protein Name Dimethylaniline monooxygenase [N-oxide-forming] 3
Protein Accession # NP_001002294
Purification Affinity Purified
Nucleotide Accession # NM_001002294
Tested Species Reactivity Human
Gene Symbol FMO3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 90%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 100%
Image 1
Human Jurkat
WB Suggested Anti-FMO3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Image 2
Human Liver Tissue
FMO3 antibody - N-terminal region (ARP44434_P050)
Catalog Number: ARP44434_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in sinusoids of liver
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
 

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