| Product Number |
ARP43754_T100 |
| Product Page |
www.avivasysbio.com/slc11a1-antibody-c-terminal-region-arp43754-t100.html |
| Name |
SLC11A1 Antibody - C-terminal region (ARP43754_T100) |
| Protein Size (# AA) |
550 amino acids |
| Molecular Weight |
61kDa |
| NCBI Gene Id |
6556 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 |
| Alias Symbols |
LSH, NRAMP, NRAMP1 |
| Peptide Sequence |
Synthetic peptide located within the following region: VLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Awomoyi,A., (2006) Int. J. Immunogenet. 33 (1), 11-15 |
| Description of Target |
SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SLC11A1 (ARP43754_T100) antibody |
| Blocking Peptide |
For anti-SLC11A1 (ARP43754_T100) antibody is Catalog # AAP43754 (Previous Catalog # AAPP25344) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SLC11A1 |
| Uniprot ID |
P49279 |
| Protein Name |
Natural resistance-associated macrophage protein 1 |
| Protein Accession # |
NP_000569 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_000578 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SLC11A1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 93% |
| Image 1 | Human lung, Human heart
 | Host: Rabbit
Target: SLC11A1
Positive control (+): Human lung (LU)
Negative control (-): Human heart (HE)
Antibody concentration: 5ug/ml |
|
| Image 2 | Human HepG2
 | WB Suggested Anti-SLC11A1 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate |
|
