ABCE1 Antibody - C-terminal region (ARP43633_P050)

Data Sheet
 
Product Number ARP43633_P050
Product Page www.avivasysbio.com/abce1-antibody-c-terminal-region-arp43633-p050.html
Name ABCE1 Antibody - C-terminal region (ARP43633_P050)
Protein Size (# AA) 599 amino acids
Molecular Weight 67kDa
NCBI Gene Id 6059
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name ATP-binding cassette, sub-family E (OABP), member 1
Alias Symbols RLI, OABP, RLI1, ABC38, RNS4I, RNASEL1, RNASELI
Peptide Sequence Synthetic peptide located within the following region: LAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Shea,P.R., (2008) Prostate 68 (4), 354-359
Description of Target ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Protein Interactions UBC; FAM96B; CIAO1; SUMO2; STAU1; DCP2; RNF2; DIABLO; PDIA3; AP1B1; PARK2; FBXO6; ILK; MMS19; ITGA4; CUL3; SIRT7; gag; UBASH3A; USP50; EIF3H; EIF3F; RNASEL; RNASE2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ABCE1 (ARP43633_P050) antibody
Blocking Peptide For anti-ABCE1 (ARP43633_P050) antibody is Catalog # AAP43633 (Previous Catalog # AAPP26605)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ABCE1
Uniprot ID P61221
Protein Name ATP-binding cassette sub-family E member 1
Sample Type Confirmation

ABCE1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_001035809
Purification Affinity Purified
Nucleotide Accession # NM_001040876
Tested Species Reactivity Human, Mouse
Gene Symbol ABCE1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Mouse liver extract
Researcher: Dr. Hao Zhu, University of Kansas Medical Center
Application: Western blotting
Species + Tissue/Cell type: Mouse liver extract
How many ug's of tissue/cell lysate run on the gel:
1. 60 ug mouse liver extract
2. 60 ug mouse liver extract
3. 60 ug mouse liver extract
Primary antibody dilution: 1:500
Secondary antibody: Anti-rabbit HRP
Secondary antibody dilution: 1:3000
Image 2
Human Jurkat
WB Suggested Anti-ABCE1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysateABCE1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
 

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