Product Number |
ARP43633_P050 |
Product Page |
www.avivasysbio.com/abce1-antibody-c-terminal-region-arp43633-p050.html |
Name |
ABCE1 Antibody - C-terminal region (ARP43633_P050) |
Protein Size (# AA) |
599 amino acids |
Molecular Weight |
67kDa |
NCBI Gene Id |
6059 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
ATP-binding cassette, sub-family E (OABP), member 1 |
Alias Symbols |
RLI, OABP, RLI1, ABC38, RNS4I, RNASEL1, RNASELI |
Peptide Sequence |
Synthetic peptide located within the following region: LAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Shea,P.R., (2008) Prostate 68 (4), 354-359 |
Description of Target |
ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. |
Protein Interactions |
UBC; FAM96B; CIAO1; SUMO2; STAU1; DCP2; RNF2; DIABLO; PDIA3; AP1B1; PARK2; FBXO6; ILK; MMS19; ITGA4; CUL3; SIRT7; gag; UBASH3A; USP50; EIF3H; EIF3F; RNASEL; RNASE2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ABCE1 (ARP43633_P050) antibody |
Blocking Peptide |
For anti-ABCE1 (ARP43633_P050) antibody is Catalog # AAP43633 (Previous Catalog # AAPP26605) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human ABCE1 |
Uniprot ID |
P61221 |
Protein Name |
ATP-binding cassette sub-family E member 1 |
Sample Type Confirmation |
ABCE1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_001035809 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001040876 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
ABCE1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Mouse liver extract
| Researcher: Dr. Hao Zhu, University of Kansas Medical Center
Application: Western blotting
Species + Tissue/Cell type: Mouse liver extract
How many ug's of tissue/cell lysate run on the gel:
1. 60 ug mouse liver extract
2. 60 ug mouse liver extract
3. 60 ug mouse liver extract
Primary antibody dilution: 1:500
Secondary antibody: Anti-rabbit HRP
Secondary antibody dilution: 1:3000 |
|
Image 2 | Human Jurkat
| WB Suggested Anti-ABCE1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Jurkat cell lysateABCE1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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