| Product Number |
ARP43519_T100 |
| Product Page |
www.avivasysbio.com/m6pr-antibody-n-terminal-region-arp43519-t100.html |
| Name |
M6PR Antibody - N-terminal region (ARP43519_T100) |
| Protein Size (# AA) |
277 amino acids |
| Molecular Weight |
28kDa |
| NCBI Gene Id |
4074 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Mannose-6-phosphate receptor (cation dependent) |
| Alias Symbols |
SMPR, MPR46, CD-MPR, MPR 46, MPR-46, CD-M6PR |
| Peptide Sequence |
Synthetic peptide located within the following region: RLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Chen,J.J., (2004) Cell 119 (7), 915-926 |
| Description of Target |
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane. |
| Protein Interactions |
FBXO6; ATP4A; SNRPGP15; HPDL; RPS28; RPL37A; RPL6; RANBP2; NDUFS4; NDUFB4; ACP2; ACOX1; GGA3; GGA1; JUN; UBC; GGA2; PLIN3; REN; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-M6PR (ARP43519_T100) antibody |
| Blocking Peptide |
For anti-M6PR (ARP43519_T100) antibody is Catalog # AAP43519 (Previous Catalog # AAPS15712) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human M6PR |
| Uniprot ID |
P20645 |
| Protein Name |
Cation-dependent mannose-6-phosphate receptor |
| Protein Accession # |
NP_002346 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_002355 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
M6PR |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 85%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-M6PR Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysate |
|
| Image 2 | Human , Mouse
 | Human, Mouse |
|
