Product Number |
ARP43518_T100 |
Product Page |
www.avivasysbio.com/got2-antibody-c-terminal-region-arp43518-t100.html |
Name |
GOT2 Antibody - C-terminal region (ARP43518_T100) |
Protein Size (# AA) |
430 amino acids |
Molecular Weight |
45kDa |
NCBI Gene Id |
2806 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) |
Description |
|
Alias Symbols |
KAT4, DEE82, KATIV, KYAT4, mitAAT |
Peptide Sequence |
Synthetic peptide located within the following region: AILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Suzuki,Y., Gene 200 (1-2), 149-156 (1997) |
Description of Target |
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. |
Protein Interactions |
FUS; UBC; NEDD8; MDM2; CDK2; CCL21; GLRX; GAPDH; APCS; AI837181; HDAC5; PSMD4; THOC7; ZDHHC6; GLUD1; HSPA8; PC; MDH2; CTNNBIP1; MPG; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-GOT2 (ARP43518_T100) antibody |
Blocking Peptide |
For anti-GOT2 (ARP43518_T100) antibody is Catalog # AAP43518 (Previous Catalog # AAPS15711) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GOT2 |
Uniprot ID |
P00505 |
Protein Name |
Aspartate aminotransferase, mitochondrial |
Publications |
Vitamin C and E Treatment Blocks Changes in Kynurenine Metabolism Triggered by Three Weeks of Sprint Interval Training in Recreationally Active Elderly Humans. Antioxidants (Basel). 10 (2021). 34573075 |
Sample Type Confirmation |
GOT2 is supported by BioGPS gene expression data to be expressed in HepG2 |
Protein Accession # |
NP_002071 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_002080 |
Tested Species Reactivity |
Human |
Gene Symbol |
GOT2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-GOT2 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysateGOT2 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
Image 2 | Human Liver
| Human Liver |
|