UBE2J1 Antibody - N-terminal region (ARP43206_T100)

• Product Number: ARP43206_T100
• Name: UBE2J1 Antibody - N-terminal region (ARP43206_T100)
• Protein Size (# AA): 318 amino acids
• Molecular Weight: 35kDa
• NCBI Gene Id: 51465
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: Ubiquitin-conjugating enzyme E2, J1, U
• Alias Symbols: UBC6, UBC6E, Ubc6p, CGI-76, NCUBE1, HSPC153, HSPC205, NCUBE-1, HSU93243
• Peptide Sequence: Synthetic peptide located within the following region: METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPD
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Lenk,U., J. Cell. Sci. 115 (PT 14), 3007-3014 (2002)
• Description of Target: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
• Protein Interactions: UBC; UBA1; MAPKAPK2; OS9; RNF5; PARK2; DIO2; SOX6; TP53; AUP1; ASNA1; DERL3; DERL1; YOD1; DERL2; FAF2; VCP; SEL1L; ELAVL1; HLA-A; BIRC2; LRSAM1; TRIM63; SYVN1; TOPORS; PJA2; RNF2; TRIM27; BRCA1; BIRC3;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-UBE2J1 (ARP43206_T100) antibody is Catalog # AAP43206 (Previous Catalog # AAPP25175)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2J1
• Uniprot ID: Q9Y385
• Protein Name: Ubiquitin-conjugating enzyme E2 J1
• Sample Type Confirmation:

  UBE2J1 is supported by BioGPS gene expression data to be expressed in Jurkat

• Protein Accession #: NP_057105
• Purification: Protein A purified
• Nucleotide Accession #: NM_016021
• Tested Species Reactivity: Human
• Gene Symbol: UBE2J1
• Predicted Species Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Zebrafish
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
• Image 1: Human Jurkat
  
  WB Suggested Anti-UBE2J1 Antibody Titration: 2.5ug/ml
  Positive Control: Jurkat cell lysateUBE2J1 is supported by BioGPS gene expression data to be expressed in Jurkat
• Image 2: Human Lung
  
  Rabbit Anti-UBE2J1 Antibody
  Catalog Number: ARP43206
  Paraffin Embedded Tissue: Human alveolar cell
  Cellular Data: Epithelial cells of renal tubule
  Antibody Concentration: 4.0-8.0 ug/ml
  Magnification: 400X
• Image 3: Human kidney
  
  Human kidney
• Image 4: Human Lung
  
  Human Lung