RNF40 Antibody - C-terminal region (ARP43165_T100)

Data Sheet
 
Product Number ARP43165_T100
Product Page www.avivasysbio.com/rnf40-antibody-c-terminal-region-arp43165-t100.html
Name RNF40 Antibody - C-terminal region (ARP43165_T100)
Protein Size (# AA) 1001 amino acids
Molecular Weight 114kDa
NCBI Gene Id 9810
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Ring finger protein 40, E3 ubiquitin protein ligase
Alias Symbols BRE1B, RBP95, STARING
Peptide Sequence Synthetic peptide located within the following region: KLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELT
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Zhu,B., (2005) Mol. Cell 20 (4), 601-611
Description of Target RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
Protein Interactions UBE2A; UBC; SFR1; CCDC146; RNF20; AMOTL2; RNF40; UBE2I; UBE2B; MSL1; MSL2; PAF1; HIST2H2BE; CDK9; MDM2; USP15; HSP90AA1; NOTCH1; UBE2E1; RB1; ITSN1; CDC73; SUMO2; ATM; AR; TERF2; TERF1; WAC; ZNF451; TRIM51; UBE2L6; NCBP1; STX1A;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-RNF40 (ARP43165_T100) antibody
Blocking Peptide For anti-RNF40 (ARP43165_T100) antibody is Catalog # AAP43165 (Previous Catalog # AAPP25134)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human RNF40
Uniprot ID O75150
Protein Name E3 ubiquitin-protein ligase BRE1B
Sample Type Confirmation

RNF40 is supported by BioGPS gene expression data to be expressed in HEK293T

Protein Accession # NP_055586
Purification Protein A purified
Nucleotide Accession # NM_014771
Tested Species Reactivity Human, Mouse
Gene Symbol RNF40
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Image 1
Human Muscle
Human Muscle
Image 2
Human 293T
WB Suggested Anti-RNF40 Antibody Titration: 1.25ug/ml
Positive Control: 293T cell lysateRNF40 is supported by BioGPS gene expression data to be expressed in HEK293T
Image 3
Adult mouse cerebellum
Sample Type:
Adult mouse cerebellum (l0x) section
Primary Antibody Dilution:
1:100
Secondary Antibody:
Donkey Anti-rabbit (568 nm)
Secondary Antibody Dilution:
1:500
Color/Signal Descriptions:
RNF40: Red DAPI:Blue
Gene Name:
RNF40
Submitted by:
Anonymous
 

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