Product Number |
ARP43165_T100 |
Product Page |
www.avivasysbio.com/rnf40-antibody-c-terminal-region-arp43165-t100.html |
Name |
RNF40 Antibody - C-terminal region (ARP43165_T100) |
Protein Size (# AA) |
1001 amino acids |
Molecular Weight |
114kDa |
NCBI Gene Id |
9810 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Ring finger protein 40, E3 ubiquitin protein ligase |
Alias Symbols |
BRE1B, RBP95, STARING |
Peptide Sequence |
Synthetic peptide located within the following region: KLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELT |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Zhu,B., (2005) Mol. Cell 20 (4), 601-611 |
Description of Target |
RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. |
Protein Interactions |
UBE2A; UBC; SFR1; CCDC146; RNF20; AMOTL2; RNF40; UBE2I; UBE2B; MSL1; MSL2; PAF1; HIST2H2BE; CDK9; MDM2; USP15; HSP90AA1; NOTCH1; UBE2E1; RB1; ITSN1; CDC73; SUMO2; ATM; AR; TERF2; TERF1; WAC; ZNF451; TRIM51; UBE2L6; NCBP1; STX1A; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-RNF40 (ARP43165_T100) antibody |
Blocking Peptide |
For anti-RNF40 (ARP43165_T100) antibody is Catalog # AAP43165 (Previous Catalog # AAPP25134) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RNF40 |
Uniprot ID |
O75150 |
Protein Name |
E3 ubiquitin-protein ligase BRE1B |
Sample Type Confirmation |
RNF40 is supported by BioGPS gene expression data to be expressed in HEK293T |
Protein Accession # |
NP_055586 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_014771 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
RNF40 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85% |
Image 1 | Human Muscle
| Human Muscle |
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Image 2 | Human 293T
| WB Suggested Anti-RNF40 Antibody Titration: 1.25ug/ml Positive Control: 293T cell lysateRNF40 is supported by BioGPS gene expression data to be expressed in HEK293T |
|
Image 3 | Adult mouse cerebellum
| Sample Type: Adult mouse cerebellum (l0x) sectionPrimary Antibody Dilution: 1:100Secondary Antibody: Donkey Anti-rabbit (568 nm)Secondary Antibody Dilution: 1:500Color/Signal Descriptions: RNF40: Red DAPI:BlueGene Name: RNF40Submitted by: Anonymous |
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