| Product Number |
ARP43055_T100 |
| Product Page |
www.avivasysbio.com/thoc4-antibody-n-terminal-region-arp43055-t100.html |
| Name |
THOC4 Antibody - N-terminal region (ARP43055_T100) |
| Protein Size (# AA) |
257 amino acids |
| Molecular Weight |
28kDa |
| Subunit |
4 |
| NCBI Gene Id |
10189 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Aly/REF export factor |
| Alias Symbols |
ALY, BEF, REF, THOC4, ALY/REF |
| Peptide Sequence |
Synthetic peptide located within the following region: GGGPIRNRPAIARGAAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Strasser,K., (2002) Nature 417 (6886), 304-308 |
| Description of Target |
THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. |
| Protein Interactions |
TP53; AKT1; NEDD1; THOC3; NCBP1; THOC2; CEP250; THOC5; DDX39B; STAU1; UBC; MDM2; SUZ12; EED; RNF2; FBXO6; CD81; ICAM1; IGSF8; PAN2; VCAM1; ITGA4; IL7R; FN1; CBX8; EIF4A3; MAGOH; PAXIP1; TRIP12; TRIP13; UBE2I; SF3B4; TLE3; YBX1; HNRNPM; ERCC4; ATP6V1E1; UB |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ALYREF (ARP43055_T100) antibody |
| Blocking Peptide |
For anti-ALYREF (ARP43055_T100) antibody is Catalog # AAP43055 (Previous Catalog # AAPP25032) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human THOC4 |
| Uniprot ID |
Q86V81 |
| Protein Name |
THO complex subunit 4 |
| Publications |
Ding, D., Enriquez-Algeciras, M., Dave, K. R., Perez-Pinzon, M. & Bhattacharya, S. K. The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis. EMBO Rep. 13, 230-6 (2012). 22261716 |
| Protein Accession # |
NP_005773 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005782 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ALYREF |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Lung
 | Human Lung |
|
| Image 2 | Human HepG2
 | WB Suggested Anti-THOC4 Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate |
|
